Abstract
Electromagnetic fields have been frequently used for diagnostics and therapy. The widely used magnetic resonance imaging (MRI) is based, directly or indirectly, upon the state of water in living tissues. However, well this fact may be known, most MR images are evaluated in terms of their structural content and not in terms of their functional information implicit in the image through the physical properties of the water. Even the basic science, represented with disciplines like biophysics and biochemistry, shows little interest regarding the participation of water in biological response(s) to applied electromagnetic fields. During these years of study, various physiological and pathophysiological states, as well as, phase specific changes in the physical properties of water were identified in the cell cycle of HeLa cells. In addition, phase specific changes in T-lymphocytes have been found to occur in response to pain and in response to pain relief. This paper presents a hypothesis that changes in the physical properties of water as well as the changes in T cell distribution “register„ the pain experience. It is also thought that magnetic be monitored and eventually predicted by viewing the physical properties of water. Reduction of pain and changes in the lymphocytes behavior under magnetic field exposure are also discussed in search of mechanism(s) explaining the therapeutic effects of magnetic fields. fields could impact on various types of pain and that the reduction of pain could
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References
Bassett, C. A. L., 1989, Fundamental and practical aspects of therapeutic uses of pulsed electromagnetic fields (PEMFs). Crit. Rev. Biomed. Engining. 17: 451–529.
Bassett, C. A. L., 1994, Therapeutic uses of electric and magnetic fields in orthopedics, in: Biological Effects of Electric and Magnetic Fields. vol 2: Beneficial and Harmful Effects. D.O. Carpenter, S.N. Ayrapetyan, eds., Academic Press, San Diego, pp: 13–48.
Baum, S., Kramer, N., Crawford, J., 2004, Health personnel antioxident study (HPAS):effects of antioxidant capacity. J. Am. Nutraceut. Assoc. 7: 25–31.
Beall, P.T., Hazlewood, C.,F., Rao, P.N., 1976, Nuclear magnetic resonance patterns of intracellular water as a function of HeLa cell cycle, Science, 192: 904–907.
Beall, P. T., Asch, B. B., Medina, D., Hazlewood, C. F., 1981, Distinction of normal, preneoplastic, and neoplastic mouse mammary cells and tissues by nuclear magnetic resonance techniques, in: The Transformed Cell. I. C. Cameron and T. B. Pool eds., Academic Press. New York, pp. 293–325.
Bernal, J., 1965, Structure of water and its biological implications, in: The State and Movement of Water in Living Organisms, Fogg ed., University Press, Cambridge. pp. 17624–627.
Bernal, J., Fowler, R., 1933, A theory of water and ionic solution, with particular reference to hydrogen and hydroxyl ions. J. Chem. Phys. 1:515–548.
Boerner, P., 2001, Functional intracellular analysis of nutritional and antioxidant status. J. Am. Nutraceut.Assoc., 4:27–41.
Bourguignon, G. and Bourguignon, L., 1989, Electrical stimulation of protein and DNA synthesis. Med Rehab 70:624–627.
Clegg, J., 1984a, Properties and metabolism of the aqueous cytoplasm and its boundaries. Am. J. Physiol., 246:R133–R151.
Clegg J., 1984b, Intracellular water and the cytomatrix: some methods of study and current views. J. Cell Biol. 99:167–171.
Damadian, R., 1971, Tumor detection by nuclear magnetic resonance. Science 171: 1151–1153.
Detlavs, I., 1987, in: Electromagnetic Therapy in Traumas and Diseases of The Support-motor Apparatus. Riga, RMI. pp. 198
Ericsson, A., Crawford, F., Hrna, D., 2002, Cellular Aging and Anti-aging Therapeutics. Explore, 11(4):32–35.
Hazlewood, C. F., 1972, Pumps or No Pumps. Science, 177:815–816.
Hazlewood, C. F., 1975. A role for water in the exclusion of cellular sodium-is a sodium pump needed? Cardiovas. Dis., Bul. of the Texas Heart Inst. 2:83–104.
Hazlewood, C., 1995, Water movement in diffusion in tissues. in: Diffusion and Perfusion: Magnetic Resonance Imaging. D. Li Bihan and B. Rosen, eds., Rana Press, New York, pp. 123-126.
Hazlewood, C., 2001, Information forgotten or overlooked: fundamental flaws in the conventional view of the living cell. Cell and Molec. Biol. 47:959–970.
Hazlewood, C., 2003, Treatment of post-polio pain with a static magnetic field and some notions on mechanism, in: Magnetotherapy: Potential Therapeutic Benefits and Adverse Effects. M. McLean, S. Engstr őm and R. Holcomb, eds.,. Floating Gallery Press, pp. 191-207.
Hazlewood, C., Nichols, B., and Chamberlain, N., 1970, The physical state of water in skeletal muscle of normal and dystrophic mice of strain 129, in: Muscle Diseases Proceedings of an International Congress, Walton, J., Canal, N., Scarlato, G. and Gleave, J. Eds., Excerpta Medica, Amsterdam, pp. 279-281.
Hazlewood, C., Van Zandt, R., 1995, A hypothesis defining an objective end point for the relief of chronic pain. Med. Hypoth. 44:63–65.
Henderson, L., 1913, in: The Fitness of the Environment; an Inquiry into the Biological Significance of the Properties of Matter, Macmillan, New York, 317 pp.
Inhofe, P. Garcia-Moral, C., 1994. Reflex sympathetic dystrophy: orthopedic immunological synapse formation. Science, 295:1539–1542.
Jerabek, J., 1994, An overview of present research in magnetotherapy. In: Proceedings of First World Congress on Magnetotherapy, R, Coghil ed., Pontypool, Lower Race, 5–78.
Lawrence, R., Rosch, P., Plowden, J., 1998, Magnet Therapy. Rocklin, CA. Prima Publishing. 241 pp.
Ling, G., 1984, in: Search of the Physical Basis of Life. Plenum Press. New York. pp 791.
Ling, G., 1992, in: A revolution in the physiology of the living cell. Krieger Publishing Company, Malabor (FL), pp: 378.
Ling, G., 2001, in: Life at the Cell and below Cell Level, Pacific Press, New York, pp 373.
Ling, G., 2003, A new theoretical foundation for the polarized-oriented multilayer theory of cell water and for inanimate systems demonstrating long-range dynamic structuring of water molecules. Physiol. Chem. Phys. & Med. NMR. 35:91–130.
Markov, M.S., 1991, Contribution of Water in the Stabilization of Biological Membranes. In: Interfacial Phenomena in Biologica Systems, M. Bender ed., Marcel Dekker, Inc., New York, pp. 153–170.
Markov, M.S., 1995, Electric current and electromagnetic field effects on soft tissues. Wounds 7:94–110.
Markov, M.S., Colbert, A., 2000. Magnetic and electromagnetic field therapy. J Back and Musculoskel. Rehab. 14:1–13.
Markov, M.S., Pilla, A.A., 1995, Electromagnetic field stimulation of soft tissues. Wounds 7:143–151.
O'Connor, M.E., Bental, R.H.C., Monaham, J.C., 1990 in: Emerging Electromagnetic Medicine, New York: Springer Verlag. 248 pp.
Pollack, G., 2001, in: Cells Gells and the Engines of Life. Ebner and Sons. Seattle, WA., pp: 305.
Pople, J., 1951, Molecular association in liquids. II. A theory of the structure of water. Proc. R. Soc. Lond. A205:163–178.
Rorschach, H., Bearden, D., Hazlewood, C., Heidorn, D., and Nicklow, R., 1987, Quasi-elastic scattering studies of water diffusion. Scanning microscopy 1(4):2043–2049.
Rorschach, H., Lin, C., Hazlewood, C., 1991, Diffusion of water in biological tissues. Scanning microscopy supplement, 5:S1–S10.
Rosch, P. and Markov, M., 2004, in: Bioelectromagnetic Medicine. Marcel Dekker, Inc. New York, pp. 851.
Schwartzman, R., McLellan, T., 1987, Reflex Sympathetic Dystrophy A Review. Arch Neurol,44:555–561.
Shive, W., 1988, Nutritional Requirements for Growth of Human Lymphocytes. Ann. Rev. Nutr. 8:81–97.
Shive, W., Pinkerton, F., Humphreys, J, et al., 1986, Development of a chemically defined serum- and protein-free medium for growth of human peripheral lymphocytes. Proc. Natl. Acad. Sci. 83:9–13.
Szent-Győrgyi, A., 1972, The Living State: With Observations On Cancer, Academic Press, New York, pp. 114.
Todorov, N., 1982, Magnetotherapy, Meditzina i Physcultura Publishing House, Sofia, pp. 106.
Trantham, E., Rorschach, H., Clegg, J., Hazlewood, C., Nicklow, R., Wakabayashi, N., 1984, Diffusive properties of water in Artemia cysts as determined from quasi-elastic neutron scattering spectra. Biophys. J. 45:927–938.
Tu, K., Matthews, R., Topek, N., et al., 1994 Glucose and insulin responses in isolated lymphocytes Reflect In Vivo status: effects of VLCD treatment. Biochem. Biophys. Res. Comm. 202:1169–1175.
Vallbona, C., Hazlewood, C.F., and Jurida, G., 1997, Response of pain to static magnetic fields in post-polio patients: a double blind pilot study. Arch. Phys. Med. and Rehabil. 78:1200–1203.
Vallbona, C., Richards, T., 1999, Evolution of magnetic therapy from alternative to traditional medicine. Physical Med. Rehab. Clinics Of North America. 10:729–754.
Verhoye, M.R., Gravenmade, E.J., Raman, E.R., et al., 1996, In Vivo noninvasive determination of abnormal water diffusion-weighted nmr imaging. Magn. Reson. Imag. 14:521–532.
von Heijne, G., 1985, Structural and thermodynamic aspects of the transfer of proteins into and across membranes. Curr. Top. Membr. Transp 24:151–179.
von Heijne, G., Blomberg, C., 1979, Trans-membrane translocation of proteins. The direct transfer model. Eur. J. Biochem. 97:175–181.
Wiener, E., Schad, L.R., Baudendistel, K. T., et al., 1996, Functional MR imaging of visual and motor cortex stimulation at high temporal resolution using a FLASH technique on a standard 1.5 tesla scanner. Magn. Res. Imaging. 14: 477–483.
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HAZLEWOOD, C., MARKOV, M., ERICSSON, A. (2006). ELECTROMAGNETIC FIELD THERAPY: A ROLE FOR WATER?. In: Ayrapetyan, S.N., Markov, M.S. (eds) BIOELECTROMAGNETICS Current Concepts. NATO Security Through Science Series. Springer, Dordrecht . https://doi.org/10.1007/1-4020-4278-7_13
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DOI: https://doi.org/10.1007/1-4020-4278-7_13
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