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Neuroblastoma

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Pediatric Surgery

Part of the book series: Springer Surgery Atlas Series ((SPRISURGERY))

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Results and Conclusion

The operative mortality is about 1–2%. For those undergoing clearance of coeliac and superior mesenteric arteries, diarrhoea has been a particular problem. At the present time age and stage are the main determinants of survival — age under 1 year and low stage are associated with an improved outcome. For those with localized tumours survival is in the region of 90–100%. The role of surgery in managing those with locally advanced or metastatic disease is unclear. However, recent evidence suggests that complete excision confers a survival advantage for those with stage 3 disease, although it is not clear that complete excision improves survival in those with metastatic disease. This remains at about 30%.

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Selected Bibliography

  • Brodeur GM, Pritchard J, Berthold F (1993) Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment. J Clin Oncol 11:1466–1477

    PubMed  CAS  Google Scholar 

  • Carachi R (2002) Perspectives on neuroblastoma. Pediatr Surg Int 18:299–305

    PubMed  Google Scholar 

  • Evans AE, Silber JH, Shpilsky A (1996) Successful management of low-stage neuroblastoma without adjuvant therapies: a comparison of two decades, 1972 through 1981 and 1982 through 1992, in a single institution. J Clin Oncol 14:2504–2510

    PubMed  CAS  Google Scholar 

  • Shorter NA, Davidoff Am, Evans AE (1995) The role of surgery in the management of stage IV neuroblastoma: a single institution study. Med Pediatr Oncol 24:287–291

    PubMed  CAS  Google Scholar 

  • Weinstein JL, Katzentein HM, Cohn SL (2003) Advances in the diagnosis and treatment of neuroblastoma. Oncologist 8:278–292

    Article  PubMed  Google Scholar 

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© 2006 Springer-Verlag Berlin Heidelberg

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Kiely, E. (2006). Neuroblastoma. In: Puri, P., Höllwarth, M.E. (eds) Pediatric Surgery. Springer Surgery Atlas Series. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30258-1_42

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  • DOI: https://doi.org/10.1007/3-540-30258-1_42

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40738-6

  • Online ISBN: 978-3-540-30258-2

  • eBook Packages: MedicineMedicine (R0)

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