Skip to main content
SpringerLink
Log in

Recent Advances in Tuberculosis Research in India

  • Chapter
  • First Online:
Biotechnology in India I

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 84))

Abstract

Tuberculosis (TB) continues to be the leading killer of mankind among all infectious diseases, especially in the developing countries. Since the discovery of tubercle bacillus more than 100 years ago, TB has been the subject of research in an attempt to develop tools and strategies to combat this disease. Research in Indian laboratories has contributed significantly towards developing the DOTS strategy employed worldwide in tuberculosis control programmes and elucidating the biological properties of its etiologic agent, M. tuberculosis. In recent times, the development of tools for manipulation of mycobacteria has given a boost to researchers working in this field. New strategies are being employed towards understanding the mechanisms of protection and pathogenesis of this disease. Molecular methods are being applied to develop new tools and reagents for prevention, diagnosis and treatment of tuberculosis. With the sequencing of the genome of M. tuberculosis, molecules are being identified for the development of new drugs and vaccines. In this chapter, the advances made in these areas by Indian researchers mainly during the last five years are reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ramakrishnan T, Chandrasekhar P (1999) J Biosci 24:143

    Article  Google Scholar 

  2. Kiple K (ed) (1993) The Cambridge World History of Human Disease. Cambridge University Press, Cambridge

    Google Scholar 

  3. Webb G (ed) (1936) Tuberculosis. Clio Medica, Paul B. Hoeber Inc., Medical Book Department of Harper & Brothers, New York

    Google Scholar 

  4. Davis AL (2000) In: Hershfield ES, Reichman LB (eds), Tuberculosis: A Comprehensive International Approach (Lung Biology in Health and Disease), vol 144. Marcel Dekker, New York, p 3

    Google Scholar 

  5. Pathania V, Almeida J, Kochi A (1997) WHO/TB/97:223

    Google Scholar 

  6. Chadha V (2000) In: Nayak R, Shaila M, Ramananda Rao G (eds), Status of Tuberculosis in India-2000. Society for Innovation and Development, Bangalore, p 19

    Google Scholar 

  7. Dye C, Scheele S, Pathania V, Raviglione M (1999) JAMA 282:677

    Article  CAS  Google Scholar 

  8. Khatri G (2000) In: Gupta S, Sood OP (eds), Tuberculosis: Proceedings of the Seventh Round Table Conference held at New Delhi. Ranbaxy Science Foundation, Gurgaon, p 15

    Google Scholar 

  9. Baily GV ( 1980) Indian J Med Res 72 Suppl:1

    Google Scholar 

  10. Tuberculosis Research Centre, Chennai (1999) Indian J Med Res 110:56

    Google Scholar 

  11. Vijay S (2000) In: Nayak R, Shaila M, Ramananda Rao G (eds), Status of Tuberculosis in India-2000. Society for Innovation and Development, Bangalore, p 91

    Google Scholar 

  12. Khatri G (1999) Indian J Tuberc 46:157

    Google Scholar 

  13. Kumar RA, Indulakshmi R, Mundayoor S (2000) Anal Biochem 286:310

    Article  CAS  Google Scholar 

  14. Kinger AK, Verma A, Tyagi JS (1993) Biotechniques 14:724

    CAS  Google Scholar 

  15. Bashyam MD, Tyagi AK (1994) Biotechniques 17:834

    CAS  Google Scholar 

  16. Amara RR, Satchidanandam V (1997) Nucleic Acids Res 25:3465

    Article  CAS  Google Scholar 

  17. Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE, 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream M-A, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Sulston JE, Taylor K, Whitehead S, Barrell BG (1998) Nature 393:537

    Article  CAS  Google Scholar 

  18. DasGupta SK, Bashyam MD, Tyagi AK (1993) J Bacteriol 175:5186

    CAS  Google Scholar 

  19. DasGupta SK, Jain S, Kaushal D, Tyagi AK (1998) Biochem Biophys Res Commun 246:797

    Article  CAS  Google Scholar 

  20. Jain S, Kaushal D, DasGupta SK, Tyagi AK (1997) Gene 190:37

    Article  CAS  Google Scholar 

  21. Kumar D, Srivastava BS, Srivastava R (1998) Vaccine 16:1212

    Article  CAS  Google Scholar 

  22. Tyagi AK, DasGupta SK, Jain S (2000) In: Hatfull G, Jacobs WJ (eds), Molecular Genetics of Mycobacteria. ASM Press, Washington, DC, p 131

    Google Scholar 

  23. Tyagi AK and colleagues, unpublished observations

    Google Scholar 

  24. Mundayoor S, personal communication

    Google Scholar 

  25. Basu A, Chawla-Sarkar M, Chakrabarti S, Das Gupta SK (2002) J Bacteriol 184:2204

    Article  CAS  Google Scholar 

  26. Chawla M, Das Gupta SK ( 1999) Plasmid 41:135

    Article  CAS  Google Scholar 

  27. Chatterjee S, Mitra M, Das Gupta SK (2000) FEMS Microbiol Lett 188:47

    Article  CAS  Google Scholar 

  28. Das Gupta SK, personal communication

    Google Scholar 

  29. Ramesh G, Gopinathan KP (1994) Gene 143:95

    Article  CAS  Google Scholar 

  30. Waskar M, Kumar D, Kumar A, Srivastava R (2000) Microbiology 146 (Pt 5):1157

    CAS  Google Scholar 

  31. Narayanan S, Sahadevan R, Narayanan PR (1997) Curr Sci 73:259

    CAS  Google Scholar 

  32. Hiriyanna KT, Ramakrishnan T (1986) Arch Microbiol 144:105

    Article  CAS  Google Scholar 

  33. Bhaduri T, Bagui TK, Sikder D, Nagaraja V (1998) J Biol Chem 273:13925

    Article  CAS  Google Scholar 

  34. Bhaduri T, Sikder D, Nagaraja V (1998) Nucleic Acids Res 26:1668

    Article  CAS  Google Scholar 

  35. Bhaduri T, Basak S, Sikder D, Nagaraja V (2000) FEBS Lett 486:126

    Article  CAS  Google Scholar 

  36. Sikder D, Nagaraja V (2000) Nucleic Acids Res 28:1830

    Article  CAS  Google Scholar 

  37. Sikder D, Nagaraja V (2001) J Mol Biol 312:347

    Article  CAS  Google Scholar 

  38. Sikder D, Unniraman S, Bhaduri T, Nagaraja V (2001) J Mol Biol 306:669

    Article  CAS  Google Scholar 

  39. Madhusudan K, Ramesh V, Nagaraja V (1994) Biochem Mol Biol Int 33:651

    CAS  Google Scholar 

  40. Madhusudan K, Nagaraja V (1995) Microbiology 141 (Pt 12):3029

    CAS  Google Scholar 

  41. Unniraman S, Nagaraja V (1999) Genes Cells 4:697

    Article  CAS  Google Scholar 

  42. Manjunatha UH, Somesh BP, Nagaraja V, Visweswariah SS (2001) FEMS Microbiol Lett 194:87

    Article  CAS  Google Scholar 

  43. Manjunatha UH, Mahadevan S, Visweswariah SS, Nagaraja V (2001) Eur J Biochem 268:2038

    Article  CAS  Google Scholar 

  44. Chatterji M, Unniraman S, Mahadevan S, Nagaraja V (2001) J Antimicrob Chemother 48:479

    Article  CAS  Google Scholar 

  45. Purnapatre K, Varshney U (1998) Eur J Biochem 256:580

    Article  CAS  Google Scholar 

  46. Purnapatre K, Handa P, Venkatesh J, Varshney U ( 1999) Nucleic Acids Res 27:3487

    Article  CAS  Google Scholar 

  47. Purnapatre K, Varshney U (1999) Eur J Biochem 264:591

    Article  CAS  Google Scholar 

  48. Handa P, Acharya N, Thanedar S, Purnapatre K, Varshney U (2000) Nucleic Acids Res 28:3823

    Article  CAS  Google Scholar 

  49. Handa P, Acharya N, Varshney U (2001) J Biol Chem 276:16992

    Article  CAS  Google Scholar 

  50. Acharya N, Varshney U (2002) Manuscript submitted

    Google Scholar 

  51. Kumar RA, Vaze MB, Chandra NR, Vijayan M, Muniyappa K (1996) Biochemistry 35:1793

    Article  CAS  Google Scholar 

  52. Vaze MB, Muniyappa K (1999) Biochemistry 38:3175

    Article  CAS  Google Scholar 

  53. Datta S, Prabu MM, Vaze MB, Ganesh N, Chandra NR, Muniyappa K, Vijayan M (2000) Nucleic Acids Res 28:4964

    Article  CAS  Google Scholar 

  54. Reddy MS, Guhan N, Muniyappa K (2001) J Biol Chem 276:45959

    Article  CAS  Google Scholar 

  55. Hemavathy KC, Nagaraja V (1995) FEMS Immunol Med Microbiol 11:291

    Article  CAS  Google Scholar 

  56. Bhargava S, Tyagi AK, Tyagi JS (1990) J Bacteriol 172:2930

    CAS  Google Scholar 

  57. Vasanthakrishna M, Kumar NV, Varshney U (1997) Microbiology 143 (Pt 11):3591

    CAS  Google Scholar 

  58. Vasanthakrishna M, Rumpal N, Varshney U (1998) J Biosci 23:101

    Article  CAS  Google Scholar 

  59. Rao AR, Varshney U (2001) Embo J 20:2977

    Article  CAS  Google Scholar 

  60. Verma A, Kinger AK, Tyagi JS (1994) Gene 148:113

    Article  CAS  Google Scholar 

  61. Verma A, Sampla AK, Tyagi JS (1999) J Bacteriol 181:4326

    CAS  Google Scholar 

  62. Ojha AK, Mukherjee TK, Chatterji D (2000) Infect Immun 68:4084

    Article  CAS  Google Scholar 

  63. Chatterji D, personal communication

    Google Scholar 

  64. Bashyam MD, Kaushal D, Dasgupta SK, Tyagi AK ( 1996) J Bacteriol 178:4847

    CAS  Google Scholar 

  65. Bashyam MD, Tyagi AK (1998) J Bacteriol 180:2568

    CAS  Google Scholar 

  66. Ramesh G, Gopinathan KP (1995) Indian J Biochem Biophys 32:361

    CAS  Google Scholar 

  67. Dastur A, Varshney U (2001) Tuberculosis (Edinb) 81:267

    Article  CAS  Google Scholar 

  68. Narayanan S, Selvakumar S, Aarati R, Vasan SK, Narayanan PR (2000) FEMS Microbiol Lett 192:263

    Article  CAS  Google Scholar 

  69. Unniraman S, Prakash R, Nagaraja V (2001) J Biol Chem 276:41850

    Article  CAS  Google Scholar 

  70. Dhar N, Rao V, Tyagi AK (2000) FEMS Microbiol Lett 190:309

    Article  CAS  Google Scholar 

  71. Anilkumar G, Chauhan MM, Ajitkumar P (1998) Gene 214:7

    Article  CAS  Google Scholar 

  72. Ajitkumar P, Anand SP, Anilkumar G, Srinivasan R (2000) In: Nayak R, Shaila MS, Ramananda Rao G (eds), Status of Tuberculosis in India-2000. Society for Innovation and Development, Bangalore, p 149

    Google Scholar 

  73. Mehrotra J, Bisht D, Tiwari VD, Sinha S (1995) Clin Exp Immunol 102:626

    CAS  Google Scholar 

  74. Mehrotra J, Mittal A, Dhindsa MS, Sinha S (1997) Clin Exp Immunol 109:446

    Article  CAS  Google Scholar 

  75. Mehrotra J, Mittal A, Rastogi AK, Jaiswal AK, Bhandari NK, Sinha S (1999) Scand J Immunol 50:411

    Article  CAS  Google Scholar 

  76. Sinha S, personal communication

    Google Scholar 

  77. Bisht D, Mehrotra J, Dhindsa MS, Singh NB, Sinha S (1996) Microbiology 142 (Pt 6):1375

    CAS  Google Scholar 

  78. Siddiqui SM, Orme IM, Saxena RK (2000) Int J Tuberc Lung Dis 4:980

    CAS  Google Scholar 

  79. Owais M, Varshney GC, Choudhry A, Chandra S, Gupta CM (1995) Antimicrob Agents Chemother 39:180

    CAS  Google Scholar 

  80. Choudhury A, Goel A, Raje M, Vohra H, Varshney GC (1997) Parasitol Res 83:746

    Article  CAS  Google Scholar 

  81. Goel A, Vohra H, Varshney GC (1999) Parasitol Res 85:19

    Article  CAS  Google Scholar 

  82. Majumdar S, Kaur H, Vohra H, Varshney GC (2000) FEMS Immunol Med Microbiol 28:71

    Article  CAS  Google Scholar 

  83. Varshney GC, personal communication

    Google Scholar 

  84. Kar SK (2000) In: Nayak R, Shaila MS, Ramananda Rao G (eds), Status of Tuberculosis in India-2000. Society for Innovation and Development, Bangalore, p 188

    Google Scholar 

  85. Hasnain SE, personal communication

    Google Scholar 

  86. Kumar D, Srivastava BS, Singh NB, Srivastava R (1996) J Clin Microbiol 34:224

    CAS  Google Scholar 

  87. Prabhakar S, Annapurna PS, Jain NK, Dey AB, Tyagi JS, Prasad HK (1998) Tuber Lung Dis 79:43

    Article  CAS  Google Scholar 

  88. Kothekar V, Raha K, Prasad HK (1998) J Biomol Struct Dyn 16:223

    CAS  Google Scholar 

  89. Prasad HK, personal communication

    Google Scholar 

  90. Pathania R, Navani NK, Rajamohan G, Dikshit KL (2002) J Biol Chem (In Press)

    Google Scholar 

  91. Nair RE, Banerjee S, Kumar S, Harinath BC (2000) Scand J Infect Dis 32:551

    Article  CAS  Google Scholar 

  92. Nair ER, Banerjee S, Kumar S, Reddy MV, Harinath BC (2001) Indian J Chest Dis Allied Sci 43:81

    CAS  Google Scholar 

  93. Banerjee SK, Bhatt K, Rana S, Misra P, Chakraborti PK ( 1996) Biochem Biophys Res Commun 226:362

    Article  CAS  Google Scholar 

  94. Banerjee SK, Misra P, Bhatt K, Mande SC, Chakraborti PK (1998) FEBS Lett 425:151

    Article  CAS  Google Scholar 

  95. Bhatt K, Banerjee SK, Chakraborti PK (2000) Eur J Biochem 267:4028

    Article  CAS  Google Scholar 

  96. Banerjee SK, Bhatt K, Misra P, Chakraborti PK (2000) Mol Gen Genet 262:949

    Article  CAS  Google Scholar 

  97. Sarin J, Aggarwal S, Chaba R, Varshney GC, Chakraborti PK (2001) J Biol Chem 276:44590

    Article  CAS  Google Scholar 

  98. Mukhopadhyay S, Chakrabarti P (1997) Antimicrob Agents Chemother 41:1721

    CAS  Google Scholar 

  99. Saha Choudhuri B, Sen S, Chakrabarti P (1999) Biochem Biophys Res Commun 256:682

    Article  Google Scholar 

  100. Basu J, Chakrabarti P, Kundu M, personal communication

    Google Scholar 

  101. Basu J, Mahapatra S, Kundu M, Mukhopadhyay S, Nguyen-Disteche M, Dubois P, Joris B, Van Beeumen J, Cole ST, Chakrabarti P, Ghuysen JM (1996) J Bacteriol 178:1707

    CAS  Google Scholar 

  102. Lepage S, Dubois P, Ghosh TK, Joris B, Mahapatra S, Kundu M, Basu J, Chakrabarti P, Cole ST, Nguyen-Disteche M, Ghuysen JM ( 1997) J Bacteriol 179:4627

    CAS  Google Scholar 

  103. Mahapatra S, Bhakta S, Ahamed J, Basu J (2000) Biochem J 350 Pt 1:75

    Article  CAS  Google Scholar 

  104. Bhakta S, Basu J (2002) Biochem J 361:635

    Article  CAS  Google Scholar 

  105. Mukhopadhyay S, Basu D, Chakrabarti P (1997) J Bacteriol 179

    Google Scholar 

  106. Saxena RK, Wiessman D, Saxena QB, Simpson J, Lewis DM (2002) Clin Exp Immunol (In Press)

    Google Scholar 

  107. Vivekanandhan A, Das S (2001) Curr Sci 81:301

    Google Scholar 

  108. Senthil Kumar KS, Raja A, Uma Devi KR, Paranjape RS (2000) Indian J Med Res 112:37

    Google Scholar 

  109. Vishwanath V, Meera R, Puvanakrishnan R, Narayanan PR (1997) Mol Cell Biochem 175:169

    Article  CAS  Google Scholar 

  110. Vishwanath V, Narayanan S, Narayanan PR ( 1998) Curr Sci 75:942

    CAS  Google Scholar 

  111. Jayashankar K, Ramanathan VD (1999) Indian J Med Res 110:91

    Google Scholar 

  112. ShakilaH, Jayashankar K, Ramanathan VD (1999) Indian J Med Res 110:4

    CAS  Google Scholar 

  113. Kamala T, Paramasivan CN, Herbert D, Venkatesan P, Prabhakar R (1996) Indian J Med Res 103:201

    CAS  Google Scholar 

  114. Bhattacharyya S, Das SN, Dey AB, Nagarkar K, Lobo J, Kapoor SK, Prasad HK (1997) J Biosci 22:99

    Article  CAS  Google Scholar 

  115. Uma H, Selvaraj P, Reetha AM, Xavier T, Prabhakar R, Narayanan PR (1999) Tuber Lung Dis 79:199

    Article  CAS  Google Scholar 

  116. Bhaskar S, Khanna SP, Mukherjee R (2000) Vaccine 18:2856

    Article  CAS  Google Scholar 

  117. Swaminathan S, Gong J, Zhang M, Samten B, Hanna LE, Narayanan PR, Barnes PF (1999) Clin Infect Dis 28:1290

    Article  CAS  Google Scholar 

  118. Swaminathan S, Nandini KS, Hanna LE, Somu N, Narayanan PR, Barnes PF (2000) Indian Pediatr 37:489

    CAS  Google Scholar 

  119. Bhattacharyya S, Singla R, Dey AB, Prasad HK (1999) Infect Immun 67:5597

    CAS  Google Scholar 

  120. Das SD, Narayanan PR, Kolappan C, Colston MJ (1998) Int J Tuberc Lung Dis 2:836

    CAS  Google Scholar 

  121. Sinha S, Mehrotra J, Bala L, Jaiswal AK, Dhawan BN (1998) Immunopharmacol Immunotoxicol 20:579

    Article  CAS  Google Scholar 

  122. Amara RR, Satchidanandam V (1996) Infect Immun 64:3765

    CAS  Google Scholar 

  123. Amara RR, Satchidanandam V (1997) Infect Immun 65:4880

    CAS  Google Scholar 

  124. Amara RR, Shanti S, Satchidanandam V (1998) Microbiology 144 (Pt 5):1197

    CAS  Google Scholar 

  125. Satchidanandam V, personal communication

    Google Scholar 

  126. Uma H, Selvaraj P, Reetha AM, Xavier T, Prabhakar R, Narayanan PR ( 1999) Indian J Med Res 109:5

    CAS  Google Scholar 

  127. Immanuel C, Swamy R, Kannapiran M, Vijayalakshmi S, Sundaram V, Jagannath K, Paramasivan CN (1997) Int J Tuberc Lung Dis 1:175

    CAS  Google Scholar 

  128. Immanuel C, Rajeswari R, Rahman F, Paul Kumaran P, Chandrasekaran V, Swamy R (2001 ) Int J Tuberc Lung Dis 5:185

    CAS  Google Scholar 

  129. Kinger AK, Tyagi JS (1993) Gene 131:113

    Article  CAS  Google Scholar 

  130. Tyagi JS, Das TK, Kinger AK (1996) Gene 177:59

    Article  CAS  Google Scholar 

  131. Tyagi JS, Kinger AK (1992) Nucleic Acids Res 20:138

    Article  CAS  Google Scholar 

  132. Dasgupta N, Kapur V, Singh KK, Das TK, Sachdeva S, Jyothisri K, Tyagi JS (2000) Tuber Lung Dis 80:141

    Article  CAS  Google Scholar 

  133. Kapur V, Sharma D, Ramanathan VD, Shakila H, Das TK, Chakravorty S, Saini DK, Li Q, Silver RF, Narayanan PR, Tyagi JS, manuscript submitted

    Google Scholar 

  134. Tyagi JS, personal communication

    Google Scholar 

  135. Saini D, Tyagi JS, manuscript submitted

    Google Scholar 

  136. Tyagi JS, Sharma D (2002) Trends Microbiol 10:68

    Article  CAS  Google Scholar 

  137. Mayuri, Bagchi G, Tyagi JS, unpublished observations

    Google Scholar 

  138. Gupta S, Tyagi AK (1993) Gene 126:157

    Article  CAS  Google Scholar 

  139. Gupta S, Jain S, Tyagi AK (1999) FEMS Microbiol Lett 172:137

    Article  CAS  Google Scholar 

  140. Tyagi AK (1998) Tuberculosis Research: Into the 21st Century. Tuberculosis Research Centre, Chennai, p 29

    Google Scholar 

  141. Kundu M, Basu J, Chakrabarti P (1989) FEBS Lett 256:207

    Article  CAS  Google Scholar 

  142. Goswami S, Sarkar S, Basu J, Kundu M, Chakrabarti P (1994) FEBS Lett 355:183

    Article  CAS  Google Scholar 

  143. Maiti D, Bhattacharyya A, Basu J (2001) J Biol Chem 276:329

    Article  CAS  Google Scholar 

  144. Chaba R, Raje M, Chakraborti PK (2002) Eur J Biochem 269:1078

    Article  CAS  Google Scholar 

  145. Koul A, Choidas A, Tyagi AK, Drlica K, Singh Y, Ullrich A (2001) Microbiology 147:2307

    CAS  Google Scholar 

  146. Chopra P, Singh A, Koul A, Ramachandran S, Drlica K, Tyagi AK, Singh Y (2002) manuscript submitted

    Google Scholar 

  147. Kaur H, Sharma S, Khuller GK (1996) Biochem Mol Biol Int 38:141

    CAS  Google Scholar 

  148. Sharma S, Giri S, Khuller GK (1998) Mol Cell Biochem 183:183

    Article  CAS  Google Scholar 

  149. Sumi MG, Mathai A, Sheela R, Radhakrishnan NS, Radhakrishnan VV, Indulakshmi R, Mundayoor S (2001) Clin Neuropathol 20:176

    CAS  Google Scholar 

  150. Parandaman V, Narayanan S, Narayanan PR (2000) Indian J Med Res 112:47

    CAS  Google Scholar 

  151. Narayanan S, Parandaman V, Rehman F, Srinivasan C, Gomathy D, Kumaraswami V, Paramasivan CN, Ramanathan VD, Narayanan PR (2000) Curr Sci 78:1367

    CAS  Google Scholar 

  152. Verma A, Rattan A, Tyagi JS (1994) Indian J Biochem Biophys 31:288

    CAS  Google Scholar 

  153. Verma A, Dasgupta N, Aggrawal AN, Pande JN, Tyagi JS (1995) Ind J Biochem Biophys 32:429

    CAS  Google Scholar 

  154. Singh KK, Muralidhar M, Kumar A, Chattopadhyaya TK, Kapila K, Singh MK, Sharma SK, Jain NK, Tyagi JS (2000) J Clin Pathol 53:355

    Article  CAS  Google Scholar 

  155. Kadival GV, D’Souza CD, Kolk AH, Samuel AM (1995) Zentralbl Bakteriol 282:353

    CAS  Google Scholar 

  156. Kadival GV, D’Souza CD, Kulkarni SP, Samuel AM (1996) Ind J Tub 43:151

    Google Scholar 

  157. Kadival GV, Kameswaran M, Ray MK (2000) Ind J Tub 47:97

    Google Scholar 

  158. Kadival GV, personal communication

    Google Scholar 

  159. Kadival GV, Kameswaran M, Doshi R, Todiwala SS, Samuel AM (1994) Zentralbl Bakteriol 281:95

    CAS  Google Scholar 

  160. Swaminathan S, Umadevi P, Shantha S, Radhakrishnan A, Datta M (1999) Ind J Pediatr 66:837

    CAS  Google Scholar 

  161. Uma Devi KR, Ramalingam B, Brennan PJ, Narayanan PR, Raja A (2001) Tuberculosis (Edinb) 81:249

    Article  CAS  Google Scholar 

  162. Raja A, Acharyulu CS, Selvarj R, Khudoos A (2001) Biomedicine 21:63

    Article  Google Scholar 

  163. Raja A, Ranganathan UD, Bethunaickan R, Dharmalingam V (2001) Pediatr Infect Dis J 20:1161

    Article  CAS  Google Scholar 

  164. Mahajan M, Singh NP, Gadre DJ, Talwar V, Gupta HC, Agarwal DS (1996) J Commun Dis 28:176

    CAS  Google Scholar 

  165. Gupta S, Bhatia R, Datta KK (1997) Tuber Lung Dis 78:21

    Article  CAS  Google Scholar 

  166. Naidu AK, Gogate A (1997) Ind J Pathol Microbiol 40:531

    CAS  Google Scholar 

  167. Choudhry V, Saxena RK (2002) Eur J Clin Microbiol Infec Dis 21:1

    Article  CAS  Google Scholar 

  168. Bhaskar S, Jain NK, Mukherjee R (1996) Tuber Lung Dis 77:160

    Article  CAS  Google Scholar 

  169. Lodam AN, Reddy MV, Narang P, Gupta OP, Harinath BC (1996) Phytochemistry 42:66

    CAS  Google Scholar 

  170. Tyagi AK, Jain S ( 1999) In: Mahajan RC, Therwath A (eds), Multidrug resistance in Emerging and Re-emerging diseases. Narosa Press, p 109

    Google Scholar 

  171. Dhar N, Rao V, Tyagi AK (2002) manuscript submitted

    Google Scholar 

  172. Singh IG, Mukherjee R, Talwar GP (1991) Vaccine 9:10

    Article  CAS  Google Scholar 

  173. Singh IG, Mukherjee R, Talwar GP, Kaufmann SH ( 1992) Infect Immun 60:257

    CAS  Google Scholar 

  174. Guleria I, Mukherjee R, Kaufmann SH (1993) Med Microbiol Immunol (Berl) 182:129

    Article  CAS  Google Scholar 

  175. Talwar GP (1999) Int Rev Immunol 18:229

    CAS  Google Scholar 

  176. Chaturvedi V, Srivastava A, Gupta HP, Srivastava BS (1999) Vaccine 17:2882

    Article  CAS  Google Scholar 

  177. Sinha RK, Verma I, Khuller GK (1997) Vaccine 15:689

    Article  CAS  Google Scholar 

  178. Sinha RK, Khuller GK (1997) Immunol Cell Biol 75:461

    Article  CAS  Google Scholar 

  179. Sharma AK, Verma I, Tewari R, Khuller GK (1999) J Med Microbiol 48:757

    Article  CAS  Google Scholar 

  180. Dhiman N, Khuller GK (1997) Med Microbiol Immunol (Berl) 186:45

    Article  CAS  Google Scholar 

  181. Dhiman N, Khuller GK (1998) FEMS Immunol Med Microbiol 21:19

    CAS  Google Scholar 

  182. Dhiman N, Khuller GK (2000) Lett Appl Microbiol 30:345

    Article  CAS  Google Scholar 

  183. Dhiman N, Sinha RK, Khuller GK (1998) Indian J Exp Biol 36:663

    CAS  Google Scholar 

  184. Chadha VK, personal communication

    Google Scholar 

  185. Chauhan R, Mande SC (2001) Biochem J 354:209

    Article  CAS  Google Scholar 

  186. Taneja B, Mande SC (2001) Protein Eng 14:391

    Article  CAS  Google Scholar 

  187. Taneja B, Mande SC (2002) Acta Crystallogr D Biol Crystallogr 58:260

    Article  CAS  Google Scholar 

  188. Gupta A, Kumar PH, Dineshkumar TK, Varshney U, Subramanya HS (2001) J Mol Biol 312:381

    Article  CAS  Google Scholar 

  189. Saikrishnan K, Jeyakanthan J, Venkatesh J, Acharya N, Purnapatre K, Sekar K, Varshney U, Vijayan M (2002) Acta Crystallogr D Biol Crystallogr 58:327

    Article  CAS  Google Scholar 

  190. Bachhawat N, Mande SC (1999) J Mol Biol 291:531

    Article  CAS  Google Scholar 

  191. Srivastava R, Kumar D, Subramaniam P, Srivastava BS (1997) Biochem Biophys Res Commun 235:602

    Article  CAS  Google Scholar 

  192. Srivastava R, Kumar D, Srivastava BS (1997) Biochem Biophys Res Commun 240:536

    Article  CAS  Google Scholar 

  193. Srivastava R, Deb DK, Srivastava KK, Locht C, Srivastava BS (1998) Biochem Biophys Res Commun 253:431

    Article  CAS  Google Scholar 

  194. Deb DK, Srivastava KK, Srivastava R, Srivastava BS (2000) Biochem Biophys Res Commun 279:457

    Article  CAS  Google Scholar 

  195. Vanaja Kumar N, Selvakumar P, Venkatesan P, Chandrasekaran V, Paramasivan CN, Prabhakar R (1998) Indian J Med Res 107:75

    Google Scholar 

  196. Ajay Kumar R, Laiza Paul K, Indulakshmi R, Manju YK, Vinod Kumar K, Ayyappan P, Joshi M, Mundayoor S (2001) Curr Sci 80:70

    Google Scholar 

  197. Balakrishnan V, Varma S, Chatterji D (2001) Curr Sci 80:1302

    CAS  Google Scholar 

  198. Sulochana S, Venkataraman P, Paramasivan CN (1999) Indian J Med Res 110:186

    CAS  Google Scholar 

  199. Mathew S, Narayanan A, Segaran R, Paramasivan CN (1999) Indian J Med Res 109:167

    CAS  Google Scholar 

  200. Venkataraman P, Herbert D, Paramasivan CN ( 1998) Indian J Med Res 108:120

    CAS  Google Scholar 

  201. Gurumurthy P, Ramachandran G, Vijayalakshmi S, Hemanth Kumar AK, Venkatesan P, Chandrasekaran V, Vijasekaran V, Kumaraswami V, Prabhakar R (1999) Int J Tuberc Lung Dis 3:119

    CAS  Google Scholar 

  202. Paramasivan CN, Kubendiran G, Herbert D ( 1998) Indian J Med Res 108:115

    CAS  Google Scholar 

  203. Selvakumar N, Kumar V, Paramasivan CN (1997) Indian JMedRes 105:58

    CAS  Google Scholar 

  204. Selvakumar N, Vanaja Kumar P, Krishnamurthy PV, Prabhakar R, Murthy PS (1997) Curr Sci 73:79

    CAS  Google Scholar 

  205. Paramasivan CN, Venkataraman P, Herbert D ( 1997) Microbios 89:135

    CAS  Google Scholar 

  206. Kamala T, Herbert D, Venkatesan P, Paramasivan CN (1997) IntJ Lepr Other Mycobact Dis 65:375

    CAS  Google Scholar 

  207. Kaur D, Khuller GK (2001) Int J Antimicrob Agents 17:51

    Article  CAS  Google Scholar 

  208. Kaur D, Verma I, Khuller GK (2001) Indian J Biochem Biophys 38:235

    CAS  Google Scholar 

  209. Kaur D, Verma I, Khuller GK (2001) Indian J Exp Biol 39:238

    CAS  Google Scholar 

  210. Sharma S, Verma I, Khuller GK (1999) Arch Microbiol 171:338

    Article  CAS  Google Scholar 

  211. Sharma S, Verma I, Khuller GK (2000) Eur Respir J 16:112

    Article  CAS  Google Scholar 

  212. Sharma S, Verma I, Khuller GK (2001) Antimicrob Agents Chemother 45:639

    Article  CAS  Google Scholar 

  213. Deol P, Khuller GK (1997) Biochim Biophys Acta 1334:161

    CAS  Google Scholar 

  214. Deol P, Khuller GK, Joshi K (1997) Antimicrob Agents Chemother 41:1211

    CAS  Google Scholar 

  215. Dutt M, Khuller GK (2001) J Antimicrob Chemother 47:829

    Article  CAS  Google Scholar 

  216. Dutt M, Khuller GK (2001) Antimicrob Agents Chemother 45:363

    Article  CAS  Google Scholar 

  217. Dutt M, Khuller GK (2001) Int J Antimicrob Agents 17:115

    Article  CAS  Google Scholar 

  218. Dutt M, Khuller GK (2001) Int J Antimicrob Agents 18:245

    Article  CAS  Google Scholar 

  219. Rajalingam R, Mehra NK, Chopra GS, Puri MM, Jain RC (1996) Tuber Lung Dis 77:502

    Article  CAS  Google Scholar 

  220. Selvaraj P, Uma H, Reetha AM, Xavier T, Prabhakar R, Narayanan PR ( 1998) Indian J Med Res 107:208

    CAS  Google Scholar 

  221. Ravikumar M, Dheenadhayalan V, Rajaram K, Lakshmi SS, Kumaran PP, Paramasivan CN, Balakrishnan K, Pitchappan RM (1999) Tuber Lung Dis 79:309

    Article  CAS  Google Scholar 

  222. Selvaraj P, Narayanan PR, Reetha AM (1999) Tuber Lung Dis 79:221

    Article  CAS  Google Scholar 

  223. Brahmajothi V, Pitchappan RM, Kakkanaiah VN, Sashidhar M, Rajaram K, Ramu S, Palanimurugan K, Paramasivan CN, Prabhakar R (1991) Tubercle 72:123

    Article  CAS  Google Scholar 

  224. Brahmajothi V (1990) Ph.D. thesis, Madurai Kamaraj University, Madurai, India

    Google Scholar 

  225. Pitchappan R, Brahmajothi V, Rajaram K, Subramanyam PT, Balakrishnan K, Muthuveeralakshmi P (1991) Tubercle 72:133

    Article  CAS  Google Scholar 

  226. Shanmugalakshmi S (2001 ) PhD thesis, Madurai Kamaraj University, Madurai, India

    Google Scholar 

  227. Brahmajothi V, Pitchappan RM, Paramasivan CN, Rajaram K, Sankakumar U, Prabhakar R (1995) The Lancet 346:790

    Article  Google Scholar 

  228. Pitchappan RM, personal communication

    Google Scholar 

  229. Mehra NK (1990) Trop Med Parasitol 41:352

    CAS  Google Scholar 

  230. Zerva L, Cizman B, Mehra NK, Alahari SK, Murali R, Zmijewski CM, Kamoun M, Monos DS (1996) J Exp Med 183:829

    Article  CAS  Google Scholar 

  231. Sharma SK, Balamurugan A, Saha PK, Pande RM, Mehra NK (2002) Am Res Cri Care Med (In press)

    Google Scholar 

  232. Mitra DK, Mehra NK, Maiti TK, Banerjee A, Taneja V, Rajalingam R, Ahuja RK, Bhattacharya BC (1995) Int J Leprosy 63:518

    CAS  Google Scholar 

  233. Mitra DK, Rajalingam R, Taneja V, Bhattacharya BC, Mehra NK (1996) Clin Immunol Immunopathol 82:60

    Article  Google Scholar 

  234. Mitra DK, De Rosa SC, Luke A, Balamurugan A, Khaitan BK, Tung J, Mehra NK, Terr AF, O’Garra A, Herzenberg LA, Roederer M (1999) Internat Immunol 11:1801

    Article  CAS  Google Scholar 

  235. Mehra NK, personal communication

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, New Delhi, 110021, India

    Anil K. Tyagi

  2. Department of Biochemistry, University of Delhi South Campus, Benito Juarez Road, New Delhi, 110021, India

    Neeraj Dhar

Authors
  1. Anil K. Tyagi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Neeraj Dhar
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. 281 SFS Apartments, Hauz Khas New Delhi, 110 016, India

    Tarun K. Ghose

  2. Birla Institute of Scientific Research, Statue Circle, Jaipur, 302 001, India

    Purnendu Ghosh

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Tyagi, A.K., Dhar, N. (2003). Recent Advances in Tuberculosis Research in India. In: Ghose, T.K., et al. Biotechnology in India I. Advances in Biochemical Engineering/Biotechnology, vol 84. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-36488-9_7

Download citation

  • DOI: https://doi.org/10.1007/3-540-36488-9_7

  • Received:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00609-1

  • Online ISBN: 978-3-540-36488-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation