Abstract
During recent years, molecular genetics have become integrated with all aspects of medicine, and advances in this area may modify clinical daily practice deeply as the basic biological mechanisms of illness are understood. The new concepts have been emerging from the knowledge obtained from the study of the human genome, and thanks to advances in computer technology and molecular engineering and new kind of probes developed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Shanley T, Wong H (2003) Molecular genetics in pediatric intensive care unit. Crit Care Clin 3:577–594
Kohli-Seth R, Oropello JM (2000) The future of bedside monitoring. Crit Care Clin 16(4):557578, vii–viii
Hopf HW (2003) Molecular diagnostics of injury and repair responses in critical illness: what is the future of ‘monitoring’ in the intensive care unit? Crit Care Med 31(8 Suppl):S518–S523
Bone RC, Grodzin CJ, Balk RA (1997) Sepsis: a new hypothesis for pathogenesis of the disease process. Chest 112:235–243
Feezor R, Moldawer L (2003) Genetic polymorphisms, functional genomics and the host inflammatory response to injury and inflammation. In: Cynober L, Moore F (eds) Nutrition and critical care, Karger AG, Basel, pp 15–37
Vincent JL (2002) The immune response in critical illness: excessive, inadequate or dysregulated. In Marshall J, Cohen J (eds) Immune response in the critically ill, Springer, Berlin Heidelberg, pp 12–21
Taneja R, Yue L, Marshall C (2002) Programmed cell death (apoptosis) and the immunologic derrangements of critical illness. In: Marshall J, Cohen J (eds) Immune response in the critically ill, Springer, Berlin, Heidelberg, pp 264–279
Ciurana C, Hack C (2002) Molecular mechanisms of complement activation during ischemia and reperfusion. In: Vincent JL (ed) Intensive Care Medicine annual update 2002. Springer, Berlin, Heidelberg, pp 39–49
Halestrap A. Toole O, Lim K (2002) The mitochondrial permeability transition: a ‘pore’ way to die. In: Evans T, Fink M, Vincent JL (eds) Mechanism of organ dysfunction in critical illness, Springer, Berlin, Heidelberg, pp 1739
Finney S, Evans T, Burke-Gaffney A (2002) Cell adhesion molecules and leukocyte trafficking in sepsis. In: Vincent JL (ed) Intensive Care Medicine annual update 2002. Springer, Berlin, Heidelberg, pp 23–38
Schwacha M, Samy A, Chaudry I (2002) Gender and cell mediated immunity following trauma, shock and sepsis. In: Vincent JL (ed) Intensive Care Medicine annual update 2002, Springer, Berlin, Heidelberg, pp 50–61
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Italia
About this chapter
Cite this chapter
Domíguez-Cherit, G., Gutiérez, J., Rivero, E. (2005). Molecular Biology in Critical Care: Is It More Than a Look Only?. In: Gullo, A., Lumb, P.D. (eds) Intensive and Critical Care Medicine. Springer, Milano. https://doi.org/10.1007/88-470-0350-4_6
Download citation
DOI: https://doi.org/10.1007/88-470-0350-4_6
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-0349-1
Online ISBN: 978-88-470-0350-7
eBook Packages: MedicineMedicine (R0)