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Analysis of Independent Households

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Design and Analysis of Vaccine Studies

Abstract

In this chapter, we consider methods of analysis that assume that the households are independent of one another. The most commonly used approach is to estimate vaccine efficacy based on the conventional secondary attack rate. We also consider the estimation of indirect effects of vaccination using household studies. The Reed–Frost model in Chapter 4 is another example of a model that assumes households or transmission units are independent.

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Correspondence to M. Elizabeth Halloran .

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© 2010 Springer Science+Business Media, LLC

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Halloran, M.E., Longini, I.M., Struchiner, C.J. (2010). Analysis of Independent Households. In: Design and Analysis of Vaccine Studies. Statistics for Biology and Health. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68636-3_12

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