Replication of eukaryotic genomes is a tightly controlled process: replication initiates at several thousand origins, whose cis-acting sequences and trans-acting proteins have been best characterized in the yeast S. cerevisiae. Despite the early successes in the identification of microbial eukaryotic origins, the available methods for origin identification in mammalian DNA have lead to the detailed characterization of only few origins, mostly because the yeast sequence determinants (ARS consensus sequences) do not seem to be evolutionarily conserved.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer
About this paper
Cite this paper
Dellino, G. (2007). Short Abstracts – Session V. In: Fagagna, F.d.d., Chiocca, S., McBlane, F., Cavallaro, U. (eds) Advances in Molecular Oncology. Advances In Experimental Medicine And Biology, vol 604. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-69116-9_14
Download citation
DOI: https://doi.org/10.1007/978-0-387-69116-9_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-69114-5
Online ISBN: 978-0-387-69116-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)