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Intracellular Pathogens and the Actin Cytoskeleton

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Actin-Binding Proteins and Disease

Part of the book series: Protein Reviews ((PRON,volume 8))

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Intracellular pathogens co-opt cellular machinery in many ways. It has long been recognized that the life cycle of most viruses depends on host cell DNA replication enzymes. More recently, intracellular bacteria as well as viruses have been discovered to disrupt and redirect the host cell cytoskeleton to assist their survival and growth. Understanding pathogen-cytoskeleton interactions will provide fresh insights into targets for drug therapies or for design of immunogens for preventive vaccine development.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Brown University Brown Medical School, Providence, RI, 02912, USA

    E. L. Bearer

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Editors and Affiliations

  1. Muscle Research Unit Bosch Institute, School of Medical Sciences, The University of Sydney, Sydney, 2006, Australia

    Cristobal G. dos Remedios

  2. Discipline of Anatomy and Histology Bosch Institute, School of Medical Sciences, The University of Sydney, Sydney, 2006, Australia

    Deepak Chhabra

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Bearer, E.L. (2008). Intracellular Pathogens and the Actin Cytoskeleton. In: dos Remedios, C.G., Chhabra, D. (eds) Actin-Binding Proteins and Disease. Protein Reviews, vol 8. Springer, New York, NY. https://doi.org/10.1007/978-0-387-71749-4_13

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