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WNT/β-Catenin Signaling in Adrenocortical Carcinoma

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Adrenocortical Carcinoma

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Abstract

The WNT/β-catenin signaling pathway plays a major role in the development of various tissues, including the adrenal cortex. β-Catenin fulfills a dual role as a structural component in cell–cell adhesion and as the key transcription cofactor of T-cell factor/lymphoid enhancer factor (TCF/LEF).

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Authors and Affiliations

  1. Endocrinology, Metabolism and Cancer Department, Institut Cochin, INSERM U567, CNRS UMR8104, Paris, France

    Sébastien Gaujoux, Frédérique Tissier & Jérôme Bertherat

  2. Department of Digestive and Endocrine Surgery, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris Descartes University, 27 Rue du Faubourg Saint-Jacques, 75014, Paris, France

    Sébastien Gaujoux

  3. Department of Pathology, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris Descartes University, Rue du Faubourg Saint-Jacques, 75014, Paris, France

    Frédérique Tissier

  4. Reference center for rare adrenal disorders, Assistance Publique Hôpitaux de Paris Hôpital Cochin, Paris Descartes University, 27 Rue du Faubourg Saint-Jacques, 75014, Paris, France

    Jérôme Bertherat

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  1. Sébastien Gaujoux
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  2. Frédérique Tissier
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  3. Jérôme Bertherat
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Correspondence to Jérôme Bertherat .

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Editors and Affiliations

  1. Zina Pitcher Place 109, Ann Arbor, 48109-2200, Michigan, USA

    Gary D. Hammer

  2. Dept. Internal Medicine, Div. Pulmonary & Critical Care Medicine, University of Michigan Health System, Zina Pitcher Place 109, Ann Arbor, 48109-2200, Michigan, USA

    Tobias Else

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Gaujoux, S., Tissier, F., Bertherat, J. (2009). WNT/β-Catenin Signaling in Adrenocortical Carcinoma. In: Hammer, G., Else, T. (eds) Adrenocortical Carcinoma. Springer, New York, NY. https://doi.org/10.1007/978-0-387-77236-3_16

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