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Hyperchloremic Metabolic Acidosis: More than Just a Simple Dilutional Effect

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Intensive Care Medicine

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Abstract

Fluid resuscitation lies at the heart of acute care medicine. Despite the central role occupied by plasma volume expansion therapeutics, there remains little consensus regarding the ideal fluid for plasma volume expansion. However, the unintended consequences of excessive plasma volume expansion as well as those untoward events directly ascribed to the prescribed fluids have come to the fore. Anasarca, pulmonary edema, myocardial stress, acute lung injury (ALI), acute kidney injury, as well as the secondary abdominal compartment syndrome have all been described as unintended consequences of plasma volume expansion following critical illness or injury [1–3]. It is important to note that these events occur with both crystalloid and colloid therapy, although at different rates.

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Author information

Authors and Affiliations

  1. Section of Trauma, Surgical Critical Care, and Surgical Emergencies, Yale University School of Medicine, 330 Cedar Street, BB-310, New Haven, CT, 06520, USA

    S. S. Abdel-Razeq & L. J. Kaplan

Authors
  1. S. S. Abdel-Razeq
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  2. L. J. Kaplan
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Universitée libre de Bruxelles, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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Abdel-Razeq, S.S., Kaplan, L.J. (2009). Hyperchloremic Metabolic Acidosis: More than Just a Simple Dilutional Effect. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-92278-2_21

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  • DOI: https://doi.org/10.1007/978-0-387-92278-2_21

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-92277-5

  • Online ISBN: 978-0-387-92278-2

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