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Regulation of Inflammation by Fas Ligand Expression on the Vascular Endothelium

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Molecular Cardiology in Clinical Practice

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 2))

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Abstract

The monolayer of endothelial cells that coat the luminal surface of the vessel wall have numerous physiological functions including the prevention of coagulation, control of vascular permeability, maintenance of vascular tone, and regulation of leukocyte extravasation. While the vascular endothelium plays a pivotal role in recruiting inflammatory cells at the site of infection or wounding, the normal endothelium is believed to serve as a barrier to inflammation in the absence of inflammatory stimuli.

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Authors and Affiliations

  1. Tufts University and St. Elizabeth’s Medical Center, USA

    Kenneth Walsh Ph.D & Masataka Sata M.D.

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  1. Kenneth Walsh Ph.D
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  2. Masataka Sata M.D.
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Editors and Affiliations

  1. Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, USA

    Michael Sanders  & John B. Kostis  & 

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© 1999 Kluwer Academic Publishers

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Walsh, K., Sata, M. (1999). Regulation of Inflammation by Fas Ligand Expression on the Vascular Endothelium. In: Sanders, M., Kostis, J.B. (eds) Molecular Cardiology in Clinical Practice. Basic Science for the Cardiologist, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38141-1_7

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  • DOI: https://doi.org/10.1007/978-0-585-38141-1_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-8602-5

  • Online ISBN: 978-0-585-38141-1

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