Abstract
It is now well-recognised that the malignant lymphomas may be complicated by involvement of the central nervous system (CNS) (Davison and Michaels, 1930; Jones, 1974; Sparling et al., 1947; Williams et al., 1959). The first case report was that of Murchison (1870) who described a case of lymphadenoma in a child in whom a tumour encroaching on the foramen magnum was found to be infiltrating the dura mater at autopsy. Shortly after the turn of the century Welch (1910) and then Guillan et al. (1925) described cord compression due to an extradural deposit of lymphoma. The first case of intracerebral lymphoma was described by Bailey (1929), although he named it perithelial sarcoma. An extensive literature has accumulated on the subject since then, and it has become clear that meningitis and extradural cord compression occur considerably more frequently than intracerebral deposits of lymphoma. Much emphasis has been placed on the relevance of the precise histological diagnosis and the presence or absence of bone marrow infiltration.
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References
Bailey, P. (1929). Intracranial sarcomatous tumors of leptomeningeal origin. Arch. Surgery, 18, 1359–1402
Brearley, R. L., Lister, T. A., Whitehouse, J. M. A. and Stansfeld, A. G. (1977). Burkitt’s lymphoma in British adults: clinical features and response to chemotherapy. Br. J. Cancer, 35, 484–7.
Bunn, P. A., Schein, P. S., Banks, P. M. and DeVita, V. T. (1976). Central nervous system complications in patients with diffuse histiocytic and undifferentiated lymphoma: leukemia revisited. Blood, 47, 3–10.
Clifford, P., Singh, S., Stjernsward, J. and Klein, G. (1967). Long term survival of patients with Burkitt’s lymphoma: An assessment of treatment and other factors which may relate to survival. Cancer Res., 27, 2578.
Davison, C. and Michaels, J. J. (1930). Lymphosarcoma with involvement of the central nervous system. Archs intern. Med., 45, 908–25.
Diamond, H. D., Williams, H. M. and Craver, L. F. (1960). The pathogenesis and management of neurological complications of malignant lymphomas and leukemia. Acta Un. Int. Contra Cancrum, 16, 831–41.
Fein, S. B. and Newill, V. A. (1954). Cerebral Hodgkin’s disease. Am. J. Med., 38, 291–4.
Friedman, K., Kim, T. H. and Panahon, A. M. (1976). Spinal cord compression in malignant lymphoma: treatment and results. Cancer, 37, 1485–91.
Gendelman, S., Rizzo, F. and Mones, R. J. (1969). Central nervous system complications of leukemic conversion of the lymphoma. Cancer, 24, 676–82.
Ginsburg, S. (1927). Hodgkin’s disease with predominant localization in the nervous system; early diagnosis and radiotherapy. Archs intern. Med., 39, 571–95.
Griffin, J. W., Thompson, R. W., Mitchinson, M. J., de Kiewiet, J. C. and Welland, F. H. (1971). Lymphomatous leptomeningitis. Am. J. Med., 51, 200–8.
Guillan, Alajouanine and Perisson. (1925). Lymphosarcome extradural metastique ayant determine une compression medullaire d’apparence primitive, d’evolution rapidement progressive; laminectomie; extirpation et radiotherapie; guerison. Bull. Mem. Soc. Med. Hop. Paris., 49, 1057.
Jackson, H. and Parker, F. (1945). Hodgkin’s disease. V. Involvement of certain other organs. New. Engl. J. Med., 233, 369–76.
Janota, I. (1966). Involvement of the nervous system in malignant lymphoma in Nigeria. Br. J. Cancer, 20, 47–61.
John, H. T. and Nabarro, J. D. N. (1955). Intracranial manifestations of malignant lymphoma. Br. J. Cancer, 9, 386–400.
Jones, A. E. (1974). In: Neurological Involvement in the Lymphomas and Leukaemias. Proc. R. Soc. Med., 67, 981–5.
Law, I. P., Dick, F. R., Blom, J. and Bergevin, P. R. (1975). Involvement of the central nervous system in non-Hodgkin’s lymphoma. Cancer, 36, 225–31.
Lister, T. A., Whitehouse, J. M. A., Beard, M. E. J., Paxton, A., Brearley, R. L., Brown, L., Wrigley, P. F. M. and Crowther, D. (1977). Early central nervous system involvement in adults with acute non-myelogenous leukaemia. Br. J. Cancer, 35, 479–83.
Lukes, R. J. and Butler, J. T. (1966). Pathology and nomenclature of Hodgkin’s disease. Cancer Res., 26, 1063–81.
Mullins, G. M., Flynn, J. P. G., El-Mandi, A. M., McQueen, J. D. and Owens, A. H. (1971). Malignant lymphoma of the spinal epidural space. Ann. intern. Med., 74, 416–23.
Murchison, C. (1870). Case of ‘lymphadenoma’ of the lymphatic system, liver, lungs, heart and dura mater. Trans. Path. Soc., Lond., 21, 372–89.
Rappaport, H. (1966). Malignant lymphomas in tumors of the hematopoietic system. Pubis Armed Forces Inst. Path., 91.
Schricker, J. L. and Smith, D. E. (1955). Primary intracerebral Hodgkin’s disease. Cancer, 8, 629–33.
Sparling, H. J. and Adams, R. D. (1946). Primary Hodgkin’s sarcoma of the brain. Archs Pathol., 42, 338–44.
Sparling, H. J., Adams, R. D. and Parker, F. (1947). Involvement of the nervous system by malignant lymphoma. Medicine, 26, 285–332.
Verda, D. J. (1944). Malignant lymphomas of the spinal epidural space. Surg. Clin. N. Am., 24, 1228–44.
Welch, J. E. (1910). Tumor of the neck showing unusual histologic features. Proc. N. Y. Path. Soc., 10, 161.
Williams, H. M., Diamond, D. H., Craver, L. F. and Parsons, H. (1959). Neurological complications of lymphomas and leukemias. Springfield, Ill., Charles C. Thomas.
Wright, D. H. (1964). Burkitt’s tumour. A postmortem study of 50 cases. Br. J. Surg., 51, 245.
Young, R. C. 1979. This volume, ch. 11, pp. 121–30.
Ziegler, J. L., Bluming, A. Z., Morrow, R. H., Fass, L. and Carbone, P. P. (1970). Central nervous system involvement in Burkitt’s lymphoma. Blood, 36, 718–28.
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© 1979 T. A. lister, S. B. J. Sutcliffe, R. L. Brearley, M. H. Cullen
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Lister, T.A., Sutcliffe, S.B.J., Brearley, R.L., Cullen, M.H. (1979). Patterns of CNS Involvement in Malignant Lymphoma. In: Whitehouse, J.M.A., Kay, H.E.M. (eds) CNS Complications of Malignant Disease. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-04285-2_12
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DOI: https://doi.org/10.1007/978-1-349-04285-2_12
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