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Haloperidol plasma levels and clinical response in schizophrenia

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Clinical Pharmacology in Psychiatry

Abstract

The recent availability of chemical techniques makes it possible to measure plasma levels of psychotropic drugs in relation to clinical response in mental disorders. Although most of the work in this area deals with tricyclic antidepressants, there is a growing interest in pharmacokinetic parameters of antipsychotic medication in schizophrenic illness.

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References

  • Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Jr, Winokur, G. and Munoz, R. (1972). Diagnostic criteria for use in psychiatric research. Archs Gen. Psychiat., 26, 57–63

    Article  CAS  Google Scholar 

  • Forsman, A. and Öhman, R. (1976). Pharmacokinetic studies of haloperidol in man. Curr. Ther. Res., 20, 319–36

    PubMed  CAS  Google Scholar 

  • Forsman, A. and Öhman, R. (1977). Applied pharmacokinetics of haloperidol in man. Curr. Ther. Res., 21, 396–411

    CAS  Google Scholar 

  • McCreadie, R. and McDonald, I. (1977). High dosage haloperidol in chronic schizophrenia. Br. J. Psychiat., 131, 310–6

    Article  CAS  Google Scholar 

  • Morselli, P. L., Bianchetti, G., Durand, G., Le Heuzey, M. F., Zarifian, E. and Dugas, M. (1979). Haloperidol plasma level monitoring in pediatric patients. Ther. Drug Monitor., 1, 35–46

    Article  CAS  Google Scholar 

  • Tune, L. E., Creese, I., De Paulo, R., Slavney, P. R., Coyle, J. T. and Snyder, S. H. (1980). Clinical state and serum neuroleptic levels measured by radioreceptor assay in schizophrenia. Am. J. Psychiat., 137, 187–90

    Article  PubMed  CAS  Google Scholar 

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Mendlewicz, J., Linkowski, P., Alexandre, J., Schoutens, A. (1981). Haloperidol plasma levels and clinical response in schizophrenia. In: Usdin, E., Dahl, S.G., Gram, L.F., Lingjærde, O. (eds) Clinical Pharmacology in Psychiatry. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-05929-4_21

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