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Regulatory aspects of S-adenosylmethionine in the periphery and CNS

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Biochemistry of S-Adenosylmethionine and Related Compounds

Abstract

S-adenosylmethionine (SAM) assumes an active role as a regulator in many biological systems in addition to its role as a cofactor in transmethylation reactions. Our interest in this nucleoside arose as a consequence of studies on the in vivo regulation of the biogenic amine enzymes, phenylethanolamine N-methyltransferase (PNMT) and hydroxyindoleamine O-methyltransferase (HIOMT).

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References

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Wong, D.L., Ciaranello, R.D. (1982). Regulatory aspects of S-adenosylmethionine in the periphery and CNS. In: Biochemistry of S-Adenosylmethionine and Related Compounds. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-06343-7_64

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