Abstract
Akathisia, a motor restlessness, is a common early side-effect of antipsychotic drugs which may occur when other signs of Parkinsonism (tremor, rigidity, hypokinesia) are not noted. Tardive dyskinesia (TD) is a late hyperkinetic side-effect of antipsychotic drugs sometimes occurring after months or years of treatment. Akathisia of late onset has recently been described and the possibility that occurrence of akathisia predicts later occurrence of TD should be further studied (Braude & Barnes, 1983; Munetz & Cornes, 1983).
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References
Braude, W.M. & Barnes, T.R.E. (1983). Late-onset akathisia — an indicant of covert dyskinesia: two case reports. Am. J. Psychiat., 140, 611–612.
Munetz, M.R. & Cornes, C.L. (1983). Distinguishing akathisia and tardive dyskinesia: a review of the literature. J. Clin. Psychopharmacol., 3, 343–350.
Seeman, P. (1981). Brain dopamine receptors. Pharmac. Rev., 32, 228–313.
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© 1986 The Contributors
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Brown, F., McRitchie, B. (1986). Neuroleptic-induced Dyskinesia in Dogs: Relative Potency of Antipsychotic Drugs in a Possible Model for Human Dyskinesias. In: Woodruff, G.N., Poat, J.A., Roberts, P.J. (eds) Dopaminergic Systems and their Regulation. Satellite Symposia of the IUPHAR 9th International Congress of Pharmacology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07431-0_46
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DOI: https://doi.org/10.1007/978-1-349-07431-0_46
Publisher Name: Palgrave Macmillan, London
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