Abstract
As part of the Second UKEMS Collaborative Study, benzidine (BZD) and its structural analogue, 4,4″-diaminoterphenyl (DAT), were examined for mutagenicity in Chinese hamster V79 cells. Initially, tests were conducted with metabolic activation using S9 samples (uninduced rat, mouse and chicken, and Aroclor 1254-induced rat) prepared for the Collaborative Study by T.M. Brooks (Shell). In light of the negative results obtained with the established mutagen/ carcinogen BZD, subsequent studies were performed using the following additional modifications to the metabolic activation system.
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© 1985 United Kingdom Environmental Mutagen Society
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O’Donovan, M.R. (1985). Mutagenicity of Benzidine and 4,4″-Diamenoterphenyl in Chinese Hamster V79 Cells. In: Parry, J.M., Arlett, C.F. (eds) Comparative Genetic Toxicology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07901-8_33
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DOI: https://doi.org/10.1007/978-1-349-07901-8_33
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