Abstract
Studies of respiratory gas tensions commonly rely on assessments of steady-state mean values. In making such assessments, variance is assumed to be the result of random fluctuation or noise of ill-defined origin. However, the existence of time-dependent changes in minute volume, which would be expected to produce changes in alveolar and arterial gas tensions, has been generally recognised since their observation in a pathological condition by Cheyne (1818) and Stokes (1854), and was probably first described by Hippocrates in the 5th century (Major, 1965).
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© 1988 The Wenner-Gren Center
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Pilsbury, D., Hibbert, G. (1988). What is ‘a Normal CO2’?. In: von Euler, C., Katz-Salamon, M. (eds) Respiratory Psychophysiology. Wenner-Gren Center International Symposium Series. Palgrave, London. https://doi.org/10.1007/978-1-349-10461-1_21
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DOI: https://doi.org/10.1007/978-1-349-10461-1_21
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