Abstract
The recognition that fetal lung maturation is dependent upon epithelial-mesenchymal interactions has led to understanding of the mechanism by which glucocorticoids accelerate fetal lung maturation. It is likely that deeper understanding of these phenomena will lead to new preventive and therapeutic approaches to respiratory distress syndrome (RDS). Tissue interactions are classified as inductive (lead to expression of a different set of genes) or permissive (no change in the set of genes being expressed, but quantitative changes in some) [1]. The corresponding cellular responses are called commitment and progression. In fetal lung development, the first occur early in development while the latter are seen near term. An interposed set of tissue interactions are less clearly characterized and are referred to as transitional.
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References
Saxen, L. Inductive tissue interactions. In: Lash, J. W. and Burger, M. M. eds. Cell and Tissue Interactions, New York: Raven Press, 1977; 1–10.
Bissell, M. J., Hall, H. G. and Parry, G. How does the extra-cellular matrix direct gene expression? J Theor Biol 1982; 99: 31–68.
Grobstein, C. Mechanism of organogenetic tissue interaction. J Natl Cancer Inst Monogr 1967; 26: 279–99.
Karkinen-Jaakelannen, M., Saxen, L. and Weiss, L. Cell Interactions in Development, New York: Academic Press, 1977.
Lash, J. W. and Burger, M. M. Cell and Tissue Interactions, New York: Raven Press, 1977.
Lash, J. W. and Whittaker, J. R. Concepts of Development, Stamford, Conn.: Simauer Associates, 1974.
Poste, G. and Nicolson, G. L. Cell Surface Reviews, Amsterdam. North-Holland, 1977.
Wessels, N. K. Tissue Interactions and Development, Menlo Park, Ca.: Benjamin/Cummings, 1977.
Hilfer, S. R. Development of terminal buds in the fetal mouse lung. Scanning Electron Microsc 1983; 3: 1387–401.
Kratochwil, K. Organ specificity in mesenchymal induction demonstrated in the embryonic development of the mammary gland of the mouse. Dev Biol 1969; 20: 46–71.
Lawson, K. A. Stage specificity in the mesenchyme requirement of rodent lung epithelium in vitro: a matter of growth control? J Embryol Exp Morphol 1983; 74: 183–206.
Taderera, J. V. Control of lung differentiation in vitro. Dev Biol 1967; 16: 489–512.
Wessels, N. K. Mammalian lung development: interactions in formation and morphogenesis of tracheal buds. J Exp Zool 1970; 175: 445–60.
Rudnick, D. Developmental capacities of the chick lung in chorioallantoic grafts. J Exp Zool 1933; 66: 125–53.
Borghese, E., Alescio, T. and Cassini, A. Experiments on induction and effect of gamma radiation in mouse lung developing in vitro. In: Rose, G. G. ed. Cinemicrography in Cell Biology, New York: Academic Press, 1963; 201–26.
Dameron, F. L’influence de divers mesenchymes sur la differentiation de l’epithelium pulmonaire de l’embryon de poulet en culture in vitro. J Embryol Exp Morphol 1961; 9: 628–33.
Sampaolo, G. and Sampaolo, L. Observations histologiques sur le poumon de foetus de Cobaye, cultive in vitro. CR Assoc Anat; 45: 707–14.
Mendelson, C. R., Johnston, J. M., MacDonald, P. C. and Snyder, J. M. Multihormonal regulation of surfactant synthesis by human fetal lung in vitro. J Clin Endocrinol Metab 1981; 53: 307–17.
Gross, I. and Wilson, C. M. Fetal rat lung maturation: initiation and modulation. J Appl Physiol: Resp Environ Exerc Physiol 1983; 55: 1725–32.
Alescio, T. and Cassini, A. Induction in vitro of tracheal buds by pulmonary mesenchyme grafted on tracheal epithelium. J Exp Zool 1962; 150: 83–94.
Spooner, B. S. and Wessels, N. K. Mammalian lung development: interactions in primordium formation and bronchial morphogenesis. J Exp Zool 1970; 175: 445–54.
Hilfer, S. R., Rayner, R. M. and Brown, J. W. Mesenchymal control of branching pattern in the fetal mouse lung. Tissue Cell 1985; 17: 523–38.
Alescio, T. and Colombo Piperno, E. A quantitative assessment of mesenchymal contribution to epithelial growth rate in mouse embryonic lung developing in vitro. J Embryol Exp Morphol 1967; 17: 213–27.
Goldin, G. V. and Wessels, N. K. Mammalian lung development: the possible role of cell proliferation in the formation of supernumerary tracheal buds and in branching morphogenesis. J Exp Zool 1979; 208: 337–46.
Avery, M. E. and Mead, J. Surface properties in relation to atelectasis and hyaline membrane disease. Am J Dis Child 1959; 97: 517–23.
Farrell, P. M. and Wood, R. E. Epidemiology of hyaline membrane disease in the United States: analysis of national mortality statistics. Pediatrics 1976; 58: 167–76.
Cheshire, L. B., Joyal, J. L., Peterson, R. D., Hester, R. B. Singh, G., Katyal, S. L. and Funkhouser, J. D. Isolation and examination of putative type II pneumocyte precursors. Pediatr Res 1987; 21: 211A (Abstr).
Funkhouser, J. D., Cheshire, L. B., Ferrara, T. B. and Peterson, R. D. A. Monoclonal antibody identification of a type II alveolar epithelial cell antigen and expression of the antigen during lung development. Dev Biol 1987; 119: 190–8.
Otto-Verberne, C. J. M. and Ten Have-Opbroek, A. A. W. Development of the pulmonary acinus in fetal rat lung: a study based on antiserum recognizing surfactant-associated proteins. Anat Embryol 1987; 175: 365–73.
Ten Have-Opbroeck, A. A. W. The development of the lung in mammals: an analysis of concepts and findings. Am J Anat 1981; 162: 201–19.
Kusakabe, M., Smith, B. T. and Post, M. Mesenchymal induction of surfactant protein expression in rat lung epithelium. Pediatr Res 1988; 23: 246A (Abstr).
Beer, D. G., Butley, M. S., Cunha, G. R. and Malkinson, A. M. Autoradiographic localization of specific (3H)dexamethasone binding in fetal lung. Dev Biol 1984; 105: 351–64.
Sweezey, N. B., Buch, S. J., Rae, S., Mawdsley, C. and Post, M. Glucocorticoid receptor and surfactant protein expression in maturing rat lung. Pediatr Res 1989; 25: 61A (Abstr).
Smith, B. T. Prevention of hyaline membrane disease: an attempt to mimic a physiologic process. In: Moss, A. ed. Pediatrics Update, New York: Elsevier North-Holland, 1979; 151–67.
Smith, B. T. Pulmonary surfactant during fetal development and neonatal adaptation: hormonal control. In: VanGolde, L. M. G. and Batenburg, J. J. eds. Pulmonary Surfactant, Amsterdam: Elsevier, 1984; 357–81.
Smith, B. T. Lung maturation in the fetal rat: acceleration by the injection of fibroblast-pneumonocyte factor. Science 1979; 20: 1094–5.
Post, M., Floros, J. and Smith, B. T Inhibition of lung maturation by monoclonal antibodies against fibroblast-pneumonocyte factor. Nature 1984; 308: 284–6.
Floros, J., Post, M. and Smith, B. T. Glucocorticoids affect the synthesis of pulmonary fibroblast-pneumonocyte factor at a pretranslational level. J Biol Chem 1985; 260: 2265–7.
Floros, J., Post, M., Kay, R. M. and Smith, B. T. Molecular basis for a pulmonary mesenchymal-epithelial interaction. In: Progress in Developmental Biology, Part B, New York: Alan R. Liss, 1986; 333–7.
Post, M., Tseu, I. and Mawdsley, C. Mesenchymal influence on surfactant protein A synthesis. Pediatr Res 1989; 25: 58A (Abstr).
Post, M., Barsoumian, A. and Smith, B. T. The cellular mechanism of glucocorticoid acceleration of fetal lung maturation: fibroblast-pneumonocyte factor stimulates cholinephosphate cytidylyltransferase activity. J Biol Chem 1986; 261: 2179–85.
Post, M., Batenburg, J. J., Schuurmans, E. A. J. M. and Van Golde, L. M. G. The rate-limiting step in the biosynthesis of phosphatidylcholine by alveolar type II cells from adult rat lung. Biochim Biophys Acta 1982; 712: 390–4.
Post, M., Batenburg, J. J., Smith, B. T. and Van Golde, L. M.G. Pool sizes of precursors for phosphatidylcholine formation in adult rat lung type II cells. Biochim Biophys Acta 1984; 795: 552–7.
Post, M., Batenburg, J. J., Van Golde, L. M. G. and Smith, B. T. The rate-limiting reaction in phosphatidylcholine synthesis by alveolar type II cells isolated from fetal rat lung. Biochim Biophys Acta 1984; 795: 558–63.
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© 1991 Macmillan Publishers Limited
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Smith, B.T. (1991). Biological approaches to the prevention of RDS. In: Cosmi, E.V., Di Renzo, G.C., Anceschi, M.M. (eds) The Surfactant System of the Lung. Palgrave, London. https://doi.org/10.1007/978-1-349-12553-1_5
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DOI: https://doi.org/10.1007/978-1-349-12553-1_5
Publisher Name: Palgrave, London
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