Abstract
The ACGT project focuses on the domain of cancer research with the ultimate objective to design, development and validation of an integrated grid-enabled platform supporting post-genomic, multi-centric clinical trials on cancer.
The purpose of this paper is to describe the role of grid technologies in the ACGT environment. The paper gives details on the grid-related parts of the ACGT system architecture and its advantages, e.g. a unified authorization framework.
In addition, two examples on how the grid environment is used within ACGT are presented: the oncosimulator, which is a standalone application that requires a lot of computational power to simulate tumor growth, and the GridR toolkit, which is a grid-enabled version of well known R environment
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Reference
ACGT (EU): http://eu-acgt.org/
Gridge Toolkit: http://www.gridge.org
Globus Toolkit: http://www.globus.org
R environment: http://www.r-project.org/
P. Farmer, H. Bonnefoi, V. Becette, M. Tubiana-Hulin, P. Fumoleau, D. Larsimont, G. Macgrogan, J. Bergh, D. Cameron, D. Goldstein, S. Duss, AL. Nicoulaz, C. Brisken, M. Fiche, M., R. Iggo, ?Identification of molecular apocrine breast tumours by microarray analysis?, Oncogene, 24, pp. 4660–4671, 2005
D. Wegener, T. Sengstag, S. Sfakianakis, S. Rping, A. Assi, ?GridR: An R-based gridenabled tool for data analysis in ACGT clinico-genomics trials?, Proc. Of the 3rd IEEE In ternational Conference on e-Science and Grid Computing, pp.228–234, 2007
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Pukacki, J., Wegener, D. (2010). Grid Technologies for Cancer Research in the ACGT Project. In: Lin, S., Yen, E. (eds) Production Grids in Asia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0046-3_8
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DOI: https://doi.org/10.1007/978-1-4419-0046-3_8
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