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Molecular Oncogenesis

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Molecular Pathology of Endocrine Diseases

Part of the book series: Molecular Pathology Library ((MPLB,volume 3))

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Abstract

Oncogenesis in all organ systems is generally considered to be an extremely complex process, with poorly understood etiology and drivers. There is substantial evidence that much of carcinogenesis is driven by changes at the molecular level, at the DNA, RNA, or the protein expression level. New evidence also suggests that alterations in small RNA molecules (microRNA) can contribute to carcinogenesis, though this process is incompletely understood. Finally, environmental, nutritional, and external factors are almost certainly linked to carcinogenesis in some organ systems. It is precisely because of the complexity in all of these widely divergent drivers of carcinogenesis that we continue to search for the causes of cancer in most organ systems.

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Authors and Affiliations

  1. Department of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA

    Jennifer L. Hunt MD, MEd (Associate Chief of Pathology, Director of Quality and Safety, Associate Professor of Pathology)

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  1. Jennifer L. Hunt MD, MEd
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Editors and Affiliations

  1. Pathology Service, WRN202, Massachusetts General Hospital, Fruit Street 55, Boston, 02114, USA

    Jennifer L. Hunt

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Hunt, J.L. (2010). Molecular Oncogenesis. In: Hunt, J. (eds) Molecular Pathology of Endocrine Diseases. Molecular Pathology Library, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1707-2_1

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  • DOI: https://doi.org/10.1007/978-1-4419-1707-2_1

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-1706-5

  • Online ISBN: 978-1-4419-1707-2

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