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Systemic Therapy for Ovarian Cancer, Current Treatment, Recent Advances, and Unmet Needs

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Emerging Therapeutic Targets in Ovarian Cancer

Abstract

Ovarian cancer is the second most common gynaecological malignancy and the leading cause of death from gynaecological cancer. Most women present with advanced disease with little prospect of cure. The optimal management of epithelial ovarian cancer involves a multidisciplinary approach incorporating surgical staging, cytoreduction, and platinum-based chemotherapy in appropriate patients. There has been little overall change in the incidence and mortality rates from ovarian cancer over the past three decades, but improvements in survival times and quality of life have occurred as a result of key advances in both surgical and chemotherapeutic strategies. In this introductory chapter, we summarise the existing treatments for epithelial ovarian cancer, introduce recent advances, and highlight unmet needs in the treatment of epithelial ovarian cancer.

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Authors and Affiliations

  1. Medical Oncology, The Royal Marsden Hospital, London, UK

    Susana Banerjee

  2. Hematology–Oncology, Arizona Cancer Center, Tucson, AZ, 85724-5024, USA

    Michael A. Bookman

  3. The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Fulham Rd, London, SW3 6JJ, UK

    Martin Gore

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  1. Susana Banerjee
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  2. Michael A. Bookman
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  3. Martin Gore
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Correspondence to Susana Banerjee .

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Editors and Affiliations

  1. Royal Marsden Hospital, Drug Development Unit, Institute of Cancer Research, Sutton, SM2 5PT, United Kingdom

    Stan Kaye

  2. , Department of Surgery and Cancer, Imperial College London, London, W12 0NN, United Kingdom

    Robert Brown

  3. , Department of Surgery and Cancer, Imperial College, London, W12 0NN, United Kingdom

    Hani Gabra

  4. , Department of Medicine, Royal Marsden Hospital, London, SW3 6JJ, United Kingdom

    Martin Gore

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Banerjee, S., Bookman, M.A., Gore, M. (2011). Systemic Therapy for Ovarian Cancer, Current Treatment, Recent Advances, and Unmet Needs. In: Kaye, S., Brown, R., Gabra, H., Gore, M. (eds) Emerging Therapeutic Targets in Ovarian Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7216-3_1

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