Abstract
The success of any PGD programme relies on there being a successful embryology laboratory for assisted conception. In addition to routine skills required as part of IVF for infertility, there are additional procedures that need to learned in order to procure an embryonic sample suitable for genetic analysis. Particularly, rigorous measures must be implemented to eliminate all possible sources of contamination of biopsied material, and to ensure segregation and accurate identification of individual embryos and the cells biopsied from them. A robust cryopreservation programme is essential to maximise success.
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Further Reading
Harton GL, Magli MC, Lundin K, Montag M, Lemmen J, Harper JC, et al. ESHRE PGD Consortium/Embryology Special Interest Group: best practice guidelines for polar body and embryo biopsy for preimplantation genetic diagnosis/screening (PGD/PGS). Hum Reprod. 2011;26:41–6.
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© 2014 Springer-Verlag London
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Bolton, V.N. (2014). Embryology and PGD. In: El-Toukhy, T., Braude, P. (eds) Preimplantation Genetic Diagnosis in Clinical Practice. Springer, London. https://doi.org/10.1007/978-1-4471-2948-6_6
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DOI: https://doi.org/10.1007/978-1-4471-2948-6_6
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