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Interactions of 4-Quinolones with Other Agents — The Importance in Assessing Practical Antibacterial Potency

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The 4-Quinolones: Anti Bacterial Agents in Vitro

Part of the book series: Springer Series in Applied Biology ((SSAPPL.BIOLOGY))

Abstract

The 4-quinolones are broad spectrum antibacterials and therefore are generally used as single antimicrobial agents. However, in certain situations, they can be combined with a second antibacterial to provide better anti-staphylococcal and anti-streptococcal activity. For example, when empirically treating febrile episodes in immunocompromised patients (Smith et al. 1988). Furthermore, it has been suggested that the 4-quinolones should be used in conjunction with a second antibacterial in order to prevent the emergence of 4-quinolone-resistant organisms during therapy (Scully et al. 1986; Farrag et al. 1986).

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Authors
  1. C. S. Lewin
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  2. J. T. Smith
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Editor information

Editors and Affiliations

  1. Department of Biology, University of York, York, YO1 5DD, UK

    Geoff C. Crumplin

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© 1990 Springer-Verlag London Limited

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Lewin, C.S., Smith, J.T. (1990). Interactions of 4-Quinolones with Other Agents — The Importance in Assessing Practical Antibacterial Potency. In: Crumplin, G.C. (eds) The 4-Quinolones: Anti Bacterial Agents in Vitro. Springer Series in Applied Biology. Springer, London. https://doi.org/10.1007/978-1-4471-3449-7_4

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  • DOI: https://doi.org/10.1007/978-1-4471-3449-7_4

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3451-0

  • Online ISBN: 978-1-4471-3449-7

  • eBook Packages: Springer Book Archive

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