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Neuroendocrine Response and Shock

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Inflammatory Response in Cardiovascular Surgery

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Abstract

The concept of shock has evolved throughout the centuries, since the early descriptions of traumatic injury. Hippocrates (460–380 BC) recognized certain principles of wound care, such as elevating an injured limb; however, at that time the correlation between blood loss and death had not yet been identified. In the twentieth century, two physiologists, Cannon and Bayliss, developed studies in laboratory animals, postulating that systemic responses resulting from severe muscle injury were caused by a toxin that caused motor tonus loss, venous blood sequestration, and hypotension [1].

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Authors and Affiliations

  1. Department of Surgery, Faculty of Medicine, University of Sao Paulo, Hospital Sao Jose, São Paulo, Brazil

    Riad N. Younes MD, PhD & Fernando C. Abrão MD

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  1. Riad N. Younes MD, PhD
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  2. Fernando C. Abrão MD
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Correspondence to Riad N. Younes MD, PhD .

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Editors and Affiliations

  1. University Nove de Julho, Melo Alves 685, São Paulo, 01417-010, São Paulo, Brazil

    Edmo Atique Gabriel

  2. Pontifícia Universidade Católica de Camp, Rodovia D. Pedro I, km 136, São Paulo, 13086-900, São Paulo, Brazil

    Sthefano Atique Gabriel

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Younes, R.N., Abrão, F.C. (2013). Neuroendocrine Response and Shock. In: Gabriel, E., Gabriel, S. (eds) Inflammatory Response in Cardiovascular Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4429-8_1

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  • DOI: https://doi.org/10.1007/978-1-4471-4429-8_1

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