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Nuclear Cardiology for Imaging the Effects of Therapy

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Nuclear Cardiology and Correlative Imaging

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Abstract

Coronary artery revascularization and medical intervention have become powerful therapies in the management of ischemic heart disease. Although coronary angiography forms the basis for much of our existing therapies for patients with known coronary artery disease (CAD), its cost and invasive nature preclude its routine and frequent use in the evaluation of all patients. Furthermore, angiography provides predominantly anatomic assessments and does not standardly assess the physiologic significance of an individual coronary stenosis. Nuclear stress imaging, with its ability to provide information about the physiologic significance of stenoses and risk stratification of CAD patients, is ideally suited to provide supplementary information to assess patients after intervention.1–3

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References

  1. Berman DS, Hachamovitch R, Kiat H, Cohen I, Cabico JA, Wang FP, et al. Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: a basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol. 1995; 26 (3): 639–647.

    Article  PubMed  CAS  Google Scholar 

  2. Hachamovitch R, Berman DS, Kiat H, Cohen I, Cabico JA, Friedman J, et al. Exercise myocardial perfusion SPECT in patients without known coronary artery disease: incremental prognostic value and use in risk stratification. Circulation. 1996; 93 (5): 905–914.

    PubMed  CAS  Google Scholar 

  3. Hachamovitch R, Berman DS, Shaw LJ, Kiat H, Cohen I, Cabico JA, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction [published erratum appears in Circulation. 1998 Jul 14;98(2):190]. Circulation. 1998; 97 (6): 535–543.

    PubMed  CAS  Google Scholar 

  4. Califf RM, Armstrong PW, Carver JR, D’Agostino RB, Strauss WE. Stratification of patients into high, medium, and low risk subgroups for purposes of risk factor management. J Am Coll Cardiol. 1996; 27: 964–1047.

    Article  Google Scholar 

  5. Gibbons RJ, Abrams J, Chatterjee K, et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina— summary article. J Am Coll Cardiol. 2003; 41: 159–168.

    Article  PubMed  Google Scholar 

  6. Miller DD, Younis LT, Bach RG, et al. Correlation of pharmacological 99mTc-sestamibi myocardial perfusion imaging with poststenotic coronary flow reserve in patients with angiographically intermediate coronary artery stenoses. Circulation. 1994; 89 (5): 2150–2160.

    PubMed  CAS  Google Scholar 

  7. Ryan TJ, Kennedy JW, Keriakes DJ, King SB III, McCallister BD, Smith SC Jr, Ullyot DJ. Guidelines for percutaneous transluminal coronary angioplasty. A report of the American Heart Association/American College of Cardiology Task Force on assessment of diagnostic and therapeutic cardiovascular procedures. Circulation. 1993; 88: 2987–3007.

    PubMed  CAS  Google Scholar 

  8. O’Rourke RA, Chaudhuri T, Shaw L, Berman DS. Resolution of stress-induced myocardial ischemia during aggressive medical therapy as demonstrated by single photon emission computed tomography imaging. Circulation. 2001; 103: 2315.

    Google Scholar 

  9. Kinlay S, Libby P, Ganz P. Endothelial function and coronary artery disease. Curr Opin Lipidol. 2001; 12 (4): 383–389.

    Article  PubMed  CAS  Google Scholar 

  10. Mostaza JM, Gomez MV, Gallardo F, et al. Cholesterol reduction improves myocardial perfusion abnormalities in patients with coronary artery disease and average cholesterol levels. J Am Coll Cardiol. 2000; 35: 76–82.

    Article  PubMed  CAS  Google Scholar 

  11. Mahmarian JJ, Fenimore NL, Marks GF, et al. Transdermal nitroglycerin patch therapy reduces the extent of exercise-induced myocardial ischemia: results of a double-blind, placebo-controlled trial using quantitative thallium-201 tomography. J Am Coll Cardiol. 1994; 24 (1): 25–32.

    Article  PubMed  CAS  Google Scholar 

  12. Dakik HA, Kleiman NS, Farmer NS, et al. Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective randomized pilot study. Circulation. 1998; 98 (19): 1985–1996.

    Google Scholar 

  13. Lauer MS, Lytle B, Pashkow F, et al. Prediction of death and myocardial infarction by screening with exercise-thallium testing after coronaryartery-bypass grafting. Lancet. 1998;351:615–622.

    Article  PubMed  CAS  Google Scholar 

  14. Lewin HC, Berman DS. Achieving sustained improvement in myocardial perfusion: role of isosorbide mononitrate. Am J Cardiol. 1997; 79 (12B): 31–35.

    Article  PubMed  CAS  Google Scholar 

  15. Parisi AF, Hartigan PM, Folland ED. Evaluation of exercise thallium scintigraphy versus exercise electrocardiography in predicting survival outcomes and morbid cardiac events in patients with single-and double-vessel disease. Findings from the Angioplasty Compared to Medicine (ACME) Study. J Am Coll Cardiol. 1997; 30 (5): 1256–1263.

    Article  PubMed  CAS  Google Scholar 

  16. Zellweger MJ, Berman D, Shaw L, et al. Evaluation of patients after intervention. In Polhost G, et al. (eds). Imaging in Cardiovascular Medicine. Philadelphia: Lippincott Williams & Wilkins; 2000.

    Google Scholar 

  17. Zellweger MJ, Lewin HC, Lai S, et al. When to stress patients after coronary artery bypass surgery? Risk stratification in patients early and late post-CABG using stress myocardial perfusion SPECT: implications of appropriate clinical strategies. J Am Coll Cardiol. 2001;37:144–152.

    Article  PubMed  CAS  Google Scholar 

  18. Zellweger MJ, Lewin H, Lai S, et al. Risk stratification in patients early and late post-CABG using stress myocardial perfusion SPECT: Implications of appropriate clinical strategies. J Am Coll Cardiol. (in press).

    Google Scholar 

  19. Mahmarian JJ, Moye LA, Verani MS, Bloom MF, Pratt CM. High reproducibility of myocardial perfusion defects in patients undergoing serial exercise thallium-201 tomography. Am J Cardiol. 1995; 75 (16): 1116–1119.

    Article  PubMed  CAS  Google Scholar 

  20. Shaw LJ, Miller DD, Berman DS, Hachamovitch R. Clinical and economic outcomes assessment in nuclear cardiology. Q J Nuc Med. 2000; 44 (2): 138–152.

    CAS  Google Scholar 

  21. Shaw LJ, Berman DS, Hachamovitch R, Heller GV, Travin M, Kesler K, Miller DD. Noninvasive strategies for the estimation of cardiac risk: An observational assessment of outcome in stable chest pain patients. Am J Cardiol. 2000; 86 (1): 1–7.

    Article  PubMed  CAS  Google Scholar 

  22. Hayes SW, Shaw LJ, O’Rourke RA, et al. COURAGE investigators. Relationship between clinical site and core lab assessments of perfusion and function on stress gated myocardial perfusion SPECT. J Am Coll Cardiol. 2001; 37: 438A.

    Article  Google Scholar 

  23. Boden WE, Weintraub WS, O’Rourke RA, et al. Review of the trials comparing medical therapy versus angioplasty and the rationale/design of the clinical outcomes utilizing percutaneous coronary revascularization and aggressive drug evaluation (COURAGE) trial. Am Heart J. 2003 (in press).

    Google Scholar 

  24. Iskander S, Pratt CM, Filipchuk NG, et al. Medical and revascularization therapies for suppression of post-infarction myocardial ischemia. Preliminary results from the Adenosine Sestamibi Post-Infarction Evaluation (INSPIRE) trial. Circulation. 2001;104:II–455.

    Google Scholar 

  25. LaRosa JC. Understanding risk in hypercholesterolemia. Clin Cardiol. 2003; 26 (1 Suppl 1): I3–6.

    Article  PubMed  Google Scholar 

  26. Yokoyama I, Ohtake T, Momomura S, et al. Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary steno-sis. Circulation. 1996; 94 (12): 3232–3238.

    PubMed  CAS  Google Scholar 

  27. Zeiher AM, Krause T, Schachinger V, et al. Impaired endothelium-dependent vasodilation of coronary resistance vessels is associated with exercise-induced myocardial ischemia. Circulation. 1995; 91: 2345–2352.

    PubMed  CAS  Google Scholar 

  28. Aoki M, Sakai K, Koyanagi S, Takeshita A, Nakamura M. Effect of nitroglycerin on coronary collateral function during exercise evaluated by quantitative analysis of thallium-201 single photon emission computed tomography. Am Heart J. 1991; 121 (5): 1361–1366.

    Article  PubMed  CAS  Google Scholar 

  29. Stegaru B, Loose R, Keller H, Buss J, Wetzel E. Effects of long-term treatment with 120 mg of sustained-release isosorbide dinitrate and 60mg of sustained-release nifedipine on myocardial perfusion. Am J Cardiol. 1988;61(9):74E–77E.

    Article  PubMed  CAS  Google Scholar 

  30. Zacca NM, Verani MS, Chahine RA, Miller RR. Effect of nifedipine on exercise-induced left ventricular dysfunction and myocardial hypoperfusion in stable angina. Am J Cardiol. 1982; 50 (4): 689–695.

    Article  PubMed  CAS  Google Scholar 

  31. Sharir T, Rabinowitz B, Chouraqui P. Antiischemic drugs reduce size of reversible defects in dipyridamole/submaximal exercise 201Tl SPECT imaging. J Nucl Cardiol. 1997; 4: S71.

    Article  Google Scholar 

  32. Shehata AR, Mascitelli VA, Herman SD, et al. Impact of acute propranolol administration on dobutamine-induced myocardial ischemia as evaluated by myocardial perfusion imaging and echocardiography. Am J Cardiol. 1997; 80: 268–272.

    Article  PubMed  CAS  Google Scholar 

  33. Cid E, Mahmarian JJ. Factors affecting the diagnostic accuracy of quantitative single photon tomography combined with dobutamine stress. J Nucl Med. 1996; 37: 58 P.

    Google Scholar 

  34. Gould KL, Ornish D, Scherwitz L, et al. Changes in myocardial perfusion abnormalities by positron emission tomography after long-term, intense risk factor modification. JAMA. 1995; 274 (11): 894–901.

    Article  PubMed  CAS  Google Scholar 

  35. Gould KL. Reversal of coronary atherosclerosis. Clinical promise as the basis for noninvasive management of coronary artery disease. Circulation. 1994; 90 (3): 1558–1571.

    PubMed  CAS  Google Scholar 

  36. Eichstadt HW, Eskotter H, Hoffman I, Amthauer HW, Weidinger G. Improvement of myocardial perfusion by short-term fluvastatin therapy in coronary artery disease. Am J Cardiol. 1995;76(2):122A–125A.

    Article  PubMed  CAS  Google Scholar 

  37. Schwartz RG, Pearson TA, Kalaria V, et al. Prospective serial evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy: coronary artery disease regression single photon emission computed tomography monitoring trial. J Am Coll Cardiol. 2003; 42: 600–610.

    Article  PubMed  CAS  Google Scholar 

  38. Guethlin M, Kasel AM, Coppenrath K, Ziegler S, Delius W, Schwaiger M. Delayed response of myocardial flow reserve to lipid-lowering therapy with fluvastatin. Circulation. 1999; 99: 475–481.

    PubMed  CAS  Google Scholar 

  39. Sdringola S, Nakagawa K, Nakagawa Y, et al. Combined intense lifestyle and pharmacologic lipid treatment further reduce coronary events and myocardial perfusion abnormalities compared with usual-care cholesterol-lowering drugs in coronary artery disease. J Am Coll Cardiol. 2003; 41: 263–272.

    Article  PubMed  CAS  Google Scholar 

  40. Alazraki NP, Krawczynska EG, Kosinski AS, et al. Prognostic value of 201Tl SPECT for patients with multivessel coronary disease postrevascularization: results from the Emory angioplasty-surgery trial. Am J Cardiol. 1999; 84 (12): 1369–1374.

    Article  PubMed  CAS  Google Scholar 

  41. Hecht HS, Shaw RE, Bruce TR, Ryan C, Stertzer SH, Myler RK. Usefulness of tomographic thallium-201 imaging for detection of restenosis after percutaneous transluminal coronary angioplasty. Am J Cardiol. 1990; 66 (19): 1314–1318.

    Article  PubMed  CAS  Google Scholar 

  42. Hecht HS, Shaw RE, Chin HL, Ryan C, Stertzer SH, Myler RK. Silent ischemia after coronary angioplasty: evaluation of restenosis and extent of ischemia in asymptomatic patients by tomo-graphic thallium-201 exercise imaging and comparison with symptomatic patients. J Am Coll Cardiol. 1991; 17 (3): 670–677.

    Article  PubMed  CAS  Google Scholar 

  43. Pfisterer M, Rickenbacher P, Kiowski W, Muller-Brand J, Burkart F. Silent ischemia after per-cutaneous transluminal coronary angioplasty: incidence and prognostic significance. J Am Coll Cardiol. 1993; 22 (5): 1446–1454.

    Article  PubMed  CAS  Google Scholar 

  44. Milan E, Zoccarato O, Terzi A, et al. Technetium99m-sestamibi SPECT to detect restenosis after successful percutaneous coronary angioplasty. J Nuc Med. 1996; 37 (8): 1300–1305.

    CAS  Google Scholar 

  45. Miller DD, Verani MS. Current status of myocardial perfusion imaging after percutaneous trans-luminal coronary angioplasty. J Am Coll Cardiol. 1994; 24 (1): 260–266.

    Article  PubMed  CAS  Google Scholar 

  46. Breisblatt WM, Barnes JV, Weiland F, Spaccavento LJ. Incomplete revascularization in multivessel percutaneous transluminal coronary angioplasty: the role for stress thallium-201 imaging. J Am Coll Cardiol. 1988; 11 (6): 1183–1390.

    Article  PubMed  CAS  Google Scholar 

  47. Manyari DE, Knudtson M, Kloiber R, Roth D. Sequential thallium-201 myocardial perfusion studies after successful percutaneous transluminal coronary artery angioplasty: delayed resolution of exercise-induced scintigraphic abnormalities. Circulation. 1988; 77 (1): 86–95.

    Article  PubMed  CAS  Google Scholar 

  48. Hirzel HO, Nuesch K, Gruentzig AR, Luetolf UM. Short-and long-term changes in myocardial perfusion after percutaneous transluminal coronary angioplasty assessed by thallium-201 exercise scintigraphy. Circulation. 1981;63:1001– 1007.

    Article  PubMed  CAS  Google Scholar 

  49. Hammermeister KE, DeRouen TA, Dodge HT, et al. Prognostic and predictive value of exertional hypotension in suspected coronary artery disease. Am J Cardiol. 1983; 51: 1261–1266.

    Article  PubMed  CAS  Google Scholar 

  50. Hachamovitch R, Berman DS, Kiat H, Cohen I, Friedman JD, Shaw LJ. Value of stress myocardial perfusion single photon emission computed tomography in patients with normal resting electrocardiograms. An evaluation of incremental prognostic value and cost-effectiveness. Circulation. 2002; 105: 823–829.

    Article  PubMed  Google Scholar 

  51. Dori G, Denekamp Y, Fishman S, Bitterman H. Exercise stress testing, myocardial perfusion imaging and stress echocardiography for detecting restenosis after successful percutaneous transluminal coronary angioplasty: a review of performance. J Intern Med. 2003; 253: 253–262.

    Article  PubMed  CAS  Google Scholar 

  52. Fischman DL, Leon M, Baim DS, et al. A randomized comparison of coronary stent placement and balloon angioplasty in the treatment of coronary artery disease. N Engl J Med. 1994; 331: 496–501.

    Article  PubMed  CAS  Google Scholar 

  53. Georgoulias P, Demakopoulos N, Kontos A, et al. 99mTc tetrofosmin myocardial perfusion imaging before and six months after percutaneous trans-luminal coronary angioplasty. Clin Nucl Med. 1998; 23: 678–682.

    Article  PubMed  CAS  Google Scholar 

  54. Galassi AR, Rosario F, Azzarelli S, et al. Usefulness of exercise tomographic myocardial perfusion imaging for detection of restenosis after coronary stent implantation. Am J Cardiol. 2000; 85: 1362–1364.

    Article  PubMed  CAS  Google Scholar 

  55. Milavetz JJ, Miller TD, Hodge DO, Holmes DR, Gibbons RJ. Accuracy of single-photon emission computed tomography myocardial perfusion imaging in patients with stents in native coronary arteries. Am J Cardiol. 1998; 82: 857–861.

    Article  PubMed  CAS  Google Scholar 

  56. Rodés-Cabau J, Candell-Riera J, Domingo E, et al. Frequency and clinical significance of myocardial ischemia detected early after coronary stent implantation. J Nucl Med. 2001;42:1768– 1772.

    PubMed  Google Scholar 

  57. Teles RC, Reis-Santos K, Gil V, et al. A negative myocardial perfusion scintigram after coronary angioplasty confers benign long-term prognosis. Rev Port Cardiol. 2002; 21: 1393–1402.

    PubMed  Google Scholar 

  58. Acampa W, Peretta M, Florimonte L, et al. Prognostic value of exercise cardiac tomography performed late after percutaneous coronary intervention in symptomatic and symptom-free patients. Am J Cardiol. 2003; 91: 259–263.

    Article  PubMed  Google Scholar 

  59. Ritchie JL, Bateman TM, Bonow RO, et al. Guidelines for clinical use of cardiac radionuclide imaging: A report of the American College of Cardiology/American Heart Association task force on assessment of diagnostic and therapeutic cardiovascular procedures (Committee on Radionuclide Imaging)—developed in collaboration with the American Society of Nuclear Cardiology. J Nucl Cardiol. 1995;Mar-Apr;2(2 Pt1): 172–192.

    Article  PubMed  CAS  Google Scholar 

  60. Serruys PW, de Jaegere P, Kiemeneij F, et al. A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group. N Engl J Med. 1994;Aug 25;331(8):489–495.

    Article  PubMed  CAS  Google Scholar 

  61. Schomig A, Kastrati A, Mudra H, et al. Four-year experience with Palmaz-Schatz stenting in coronary angioplasty complicated by dissection with threatened or present vessel closure. Circulation. 1994;Dec;90(6): 2716–2724.

    PubMed  CAS  Google Scholar 

  62. Fenton SH, Fischman DL, Savage MP, et al. Long-term angiographic and clinical outcome after implantation of balloon-expandable stents in aortocoronary saphenous vein grafts. Am J Cardiol. 1994;Dec 15;74(12):1187–1191.

    Article  PubMed  CAS  Google Scholar 

  63. Morice MC, Serruys PW, Sousa JE, et al., and the RAVEL Study Group. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med. 2002;Jun 6;346(23):1773–1780.

    Article  PubMed  CAS  Google Scholar 

  64. Garzon PP, Eisenberg MJ. Functional testing for the detection of restenosis after percutaneous transluminal coronary angioplasty: a meta-analysis. Can J Cardiol. 2001;Jan;17 (1): 41–48.

    CAS  Google Scholar 

  65. Cottin Y, Rezaizadeh K, Touzery C, et al. Longterm prognostic value of 201Tl single-photon emission computed tomographic myocardial perfusion imaging after coronary stenting. Am Heart J. 2001;Jun;141 (6): 999–1006.

    Article  PubMed  CAS  Google Scholar 

  66. Stempfle HU, Schmid R, Tausig A, et al. Early detection of myocardial microcirculatory disturbances after primary PTCA in patients with acute myocardial infarction: coronary blood flow velocity versus sestamibi perfusion imaging. Z Kardiol. 2002;91 Suppl 3:126–131.

    Article  PubMed  CAS  Google Scholar 

  67. Fram DB, Azar RR, Ahlberg AW, et al. Duration of abnormal SPECT myocardial perfusion imaging following resolution of acute ischemia: an angioplasty model. J Am Coll Cardiol. 2003; Feb 5;41(3):452–459.

    Article  PubMed  Google Scholar 

  68. Jaffe R, Haim SB, Karkabi B, et al. Myocardial perfusion abnormalities early (12–24h) after coronary stenting or balloon angioplasty: implications regarding pathophysiology and late clinical outcome. Cardiology. 2002; 98 (1–2): 60–66.

    Article  PubMed  Google Scholar 

  69. Lauer MS, Lytle B, Pashkow F, Snader CE, Marwick TH. Prediction of death and myocardial infarction by screening with exercise-thallium testing after coronary-artery-bypass grafting. Lancet. 1998; 351: 615–622.

    Article  PubMed  CAS  Google Scholar 

  70. Miller TD, Christian TF, Hodge DO, et al. Prognostic value of exercise thallium-201 imaging performed within 2 years of coronary artery bypass graft surgery. J Am Coll Cardiol. 1998; 31 (4): 848–854.

    Article  PubMed  CAS  Google Scholar 

  71. Desideri A, Candelpergher G, Zanco P, et al. Exercise technetium 99m sestamibi single-photon emission computed tomography late after coronary bypass surgery: long-term follow-up. Clin Cardiol. 1997;20(9):779–784.

    Article  PubMed  CAS  Google Scholar 

  72. Elhendy A, Cornel JH, Domburg RT, et al. Effect of coronary artery bypass surgery on myocardial perfusion and ejection fraction response to inotropic stimulation in patients without improvement in resting ejection fraction. Am J Cardiol. 2000; 86: 490–494.

    Article  PubMed  CAS  Google Scholar 

  73. Kjaer A, Meyer C, Nielsen FS, Parving HH, Hesse B. Dipyridamole, cold pressor test and demonstration of endothelial dysfunction: a PET study of myocardial perfusion in diabetes. J Nucl Med. 2003; 44: 19–23.

    PubMed  CAS  Google Scholar 

  74. Kosa I, Blasini R, Schneider-Eicke J, et al. Early recovery of coronary flow reserve after stent implantation as assessed by positron emission tomography. J Am Coll Cardiol. 1999; 34 (4): 1036–1041.

    Article  PubMed  CAS  Google Scholar 

  75. Fleming RM, Harrington GM. Quantitative coronary arteriography and its assessment of atherosclerosis. Part 1. Examining the independent variables. Angiology. 1994; 45: 829–833.

    Article  PubMed  CAS  Google Scholar 

  76. Fleming RM, Harrington GM. Quantitative coronary arteriography and its assessment of atherosclerosis. Part 2. Calculating stenosis flow reserve directly from percent diameter stenosis. Angiology. 1994; 45: 835–840.

    Article  PubMed  CAS  Google Scholar 

  77. Fleming RM, Boyd L, Forster M. Angina is caused by regional blood flow differences-proof of a physiologic (not anatomic) narrowing. Joint ACC-ESC Session, 49th Annual Scientific Sessions, Anaheim, CA 12 March 2000.

    Google Scholar 

  78. Caramori PR, Lima VC, Seidelin PH, Newton GE, Parker JD, Adelman AG. Long term endothelial dysfunction after coronary artery stenting. J Am Coll Cardiol. 1999; 34: 1675–1679.

    Article  PubMed  CAS  Google Scholar 

  79. Kern MJ, Puri S, Bach RG, et al. Abnormal coronary flow abnormality reserve after coronary stenting in patients: role of relative coronary reserve to assess potential mechanisms. Circulation. 1999; 100: 2491–2498.

    PubMed  CAS  Google Scholar 

  80. Versaci F, Gaspardone A, Tomai F, et al. Chest pain after coronary artery stent implantation. Am J Cardiol. 2002; 89: 500–504.

    Article  PubMed  Google Scholar 

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Authors
  1. Leslee J. Shaw
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  2. Gary V. Heller
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Editor information

Editors and Affiliations

  1. Department of Medicine, Federal University of Paraná Medical School, 80050-010, Curitiba, Paraná, Brazil

    João V. Vitola MD, PhD (Associate Professor, Director) (Associate Professor, Director)

  2. Quanta Medicina Nuclear, 80050-010, Curitiba, Paraná, Brazil

    João V. Vitola MD, PhD (Associate Professor, Director) (Associate Professor, Director)

  3. Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, 37232, Nashville, TN, USA

    Dominique Delbeke MD, PhD (Professor and Director of Nuclear Medicine and PET) (Professor and Director of Nuclear Medicine and PET)

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Shaw, L.J. et al. (2004). Nuclear Cardiology for Imaging the Effects of Therapy. In: Vitola, J.V., Delbeke, D. (eds) Nuclear Cardiology and Correlative Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2038-1_10

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  • DOI: https://doi.org/10.1007/978-1-4612-2038-1_10

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