Abstract
Percutaneous transluminal angioplasty using a balloon catheter has been widely used in the treatment of obstructing lesions in the coronary, visceral and peripheral arteries. While the clinical usefulness of this procedure is well established, the precise mechanism by which enlargement of the arterial lumen is achieved has been poorly understood. In their original description of transluminal angioplasty using a rigid coaxial catheter system, Dotter and Judkins attributed the effectiveness of their procedure to compression of the atheromatous plaque against a relatively unyield-artery wall (1). This mechanism was subsequently endorsed by Andreas Gruntzig, the developer of the balloon catheter technique of angioplasty (2) and accepted by most clinicians utilizing the procedure. However, the concept of plaque compression or of herniation of atheromatous intima into the artery wall was not supported by histologic or other morphologic evidence and could not be reconciled with the physical incompressibility of solid and liquid plaque material.
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References
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© 1990 Springer-Verlag New York Inc.
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Zarins, C.K. (1990). Histologic and Functional Basis for Ameliorating Plaques by Percutaneous Transluminal Angioplasty. In: Glagov, S., Newman, W.P., Schaffer, S.A. (eds) Pathobiology of the Human Atherosclerotic Plaque. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3326-8_38
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DOI: https://doi.org/10.1007/978-1-4612-3326-8_38
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