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Oxygen Tension in the Clinical Situation

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Oxygen and Living Processes

Part of the book series: Topics in Environmental Physiology and Medicine ((TEPHY))

Abstract

The importance of hemoglobin oxygenation has long been appreciated and the clinical measurement of it in the 1930s became markedly easier as a result of the work by Millikan (1933) who introduced the photocell oximeter. This instrument allowed not only rapid estimates of oxygen saturation of blood in vitro, but also permitted continuous in vivo measurements by transillumination of the lobe of the ear. Although at that time it was appreciated that hemoglobin saturation was related to oxygen tension and oxygen hemoglobin association/dissociation curves were available, it does not appear to have been widely understood clinically until relatively recently that the oxygen tension of the blood is often more important to the survival of the tissue than the oxygen content. Furthermore, even among physiologists it was assumed that mixed venous blood oxygen tension could be equated with a rather homogeneous average tissue \({P_{{O_2}}}\).

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Authors
  1. I. A. Silver
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Editors and Affiliations

  1. Marine Biological Laboratory, 02543, Woods Hole, Massachusetts, USA

    Daniel L. Gilbert Ph.D.

  2. Laboratory of Biophysics, NINCDS National Institutes of Health, Bethesda, Maryland, 20205, USA

    Daniel L. Gilbert Ph.D.

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Silver, I.A. (1981). Oxygen Tension in the Clinical Situation. In: Gilbert, D.L. (eds) Oxygen and Living Processes. Topics in Environmental Physiology and Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5890-2_16

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  • DOI: https://doi.org/10.1007/978-1-4612-5890-2_16

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-5892-6

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