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Sister Chromatid Exchanges Induced by Photodynamic Treatment of Cells in The Presence of Photofrin II, Aluminium Phthalocyanine Tetrasulfonate and Tetra(3-Hydroxyphenyl)Porphyrin

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Light in Biology and Medicine

Abstract

The cellular effects and clinical applicability of photodynamic treatment (PDT) using hematoporphyrin derivative (HpD) or Photofrin II (PII) as photosensitizers have been extensively studied over the last years. The method is based on the partially selective retention of the sensitizers in tumor tissue and their photodynamic effects, which are mediated mainly through formation of singlet oxygen.

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© 1988 Plenum Press, New York

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Berg, K., Hovig, E., Moan, J. (1988). Sister Chromatid Exchanges Induced by Photodynamic Treatment of Cells in The Presence of Photofrin II, Aluminium Phthalocyanine Tetrasulfonate and Tetra(3-Hydroxyphenyl)Porphyrin. In: Douglas, R.H., Moan, J., Dall’Acqua, F. (eds) Light in Biology and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0709-9_13

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  • DOI: https://doi.org/10.1007/978-1-4613-0709-9_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8043-9

  • Online ISBN: 978-1-4613-0709-9

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