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Relationship Between Structure and Metabolism of HDL Apolipoproteins; Study with Synthetic Peptides

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Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 243))

Abstract

In blood, lipids are transported in complex structures referred to as lipoproteins. These are formed of a monomolecular surface of phospholipids surrounding a core of neutral lipids (cholesterol esters and triglycerides)1. The polar phospholipid surface contains unesterified cholesterol and apolipoproteins. Apolipoproteins play several roles which may be summarized as follows:

  • They participate to the structural stability and to the solubility of lipoprotein particles.

  • Certain apolipoproteins act as effectors of lipolytic enzymes2,3.

  • Apolipoproteins may be recognized by specific receptors4–7.

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Author information

Authors and Affiliations

  1. INSERM U. 197, Laboratoire de Métabolisme des Lipides, Hopital de 1’Antiquaille, Lyon, France

    Gabriel Ponsin

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  1. Gabriel Ponsin
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Editors and Affiliations

  1. Research Foundation on Atherosclerosis, Brussels, Belgium

    Claude L. Malmendier

  2. The Free University of Brussels, Brussels, Belgium

    Claude L. Malmendier

  3. Lipoprotein and Atherosclerosis Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

    Petar Alaupovic

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© 1988 Plenum Press, New York

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Ponsin, G. (1988). Relationship Between Structure and Metabolism of HDL Apolipoproteins; Study with Synthetic Peptides. In: Malmendier, C.L., Alaupovic, P. (eds) Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis. Advances in Experimental Medicine and Biology, vol 243. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0733-4_17

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  • DOI: https://doi.org/10.1007/978-1-4613-0733-4_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8055-2

  • Online ISBN: 978-1-4613-0733-4

  • eBook Packages: Springer Book Archive

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