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Specificity and Function of T Lymphocytes Induced by Influenza A Viruses

  • Chapter
The Influenza Viruses

Part of the book series: The Viruses ((VIRS))

Abstract

Over the past 20 years, it has become increasingly clear that thymus-derived lymphocytes (T lymphocytes) play a pivotal role in immune responsiveness. Perhaps nowhere is this more apparent than in antiviral immunity, in which T lymphocytes provide a critical helper function in antibody responses and also function directly to reduce viral replication. Of the large number of viruses known to elicit T-lymphocyte responses, influenza virus has been the most extensively studied.

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Authors and Affiliations

  1. National Institute of Allergy and Infectious Diseases, Laboratory of Viral Diseases, National Institutes of Health, Rockville, Maryland, 20852, USA

    Jonathan W. Yewdell

  2. Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, 19104, USA

    Charles J. Hackett

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  1. Jonathan W. Yewdell
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  1. Graduate Program in Molecular Biology, Memorial Sloan-Kettering Cancer Center, 10021, New York, New York, USA

    Robert M. Krug

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Yewdell, J.W., Hackett, C.J. (1989). Specificity and Function of T Lymphocytes Induced by Influenza A Viruses. In: Krug, R.M. (eds) The Influenza Viruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0811-9_8

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