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Recent Developments in the Prompt-Gamma Total Body Nitrogen Measurement Facility of the Toronto General Hospital

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In Vivo Body Composition Studies

Part of the book series: Basic Life Sciences ((BLSC,volume 55))

Abstract

The measurement of body nitrogen by neutron activation analysis provides a measure of protein status, using the constant numerical relationship of 6.25 between nitrogen and body protein. Measurements of nitrogen balance have been used routinely for studying changes of total body nitrogen (TBN). However, a method to measure total body protein (TBP), itself, is required to assess protein status of an individual, resulting from disease or from treatment. TBP has been clinically very useful in several studies, e.g. obesity following calorie restriction (Stallings et al., 1988), ascites following peritoneovenous shunting (Blendis et al., 1986), renal failure following the start of treatment by continuous ambulatory peritoneal dialysis (Schilling et al., 1985), cancer (Shike et al.. 1984) and (malabsorption following total parenteral nutrition (McNeill et al., 1982).

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© 1990 Plenum Press, New York

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Krishnan, S.S., McNeill, K.G., Harrison, J.E. (1990). Recent Developments in the Prompt-Gamma Total Body Nitrogen Measurement Facility of the Toronto General Hospital. In: Yasumura, S., Harrison, J.E., McNeill, K.G., Woodhead, A.D., Dilmanian, F.A. (eds) In Vivo Body Composition Studies. Basic Life Sciences, vol 55. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1473-8_42

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  • DOI: https://doi.org/10.1007/978-1-4613-1473-8_42

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8780-3

  • Online ISBN: 978-1-4613-1473-8

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