Abstract
It is well-known that the alicyclic amine derivatives of cisplatin are less toxic as the ring size increases from cyclo-propylamine to cyclohexylamine, whereas the antitumour activity remains largely unalterated (1). Nevertheless the cyclopentylamine complex shows a larger spectrum of activity than the cyclohexylamine analog.
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© 1988 Martinus Nijhoff Publishing, Boston
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Scarcia, V., Furlani, A., Papaioannou, A., Craciunescu, D.G., Doadrio, A. (1988). Cytostatic and Antitumour Properties for a New Series of Pt(II) Complexes with Cyclopentylamine. In: Nicolini, M. (eds) Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Developments in Oncology, vol 54. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1717-3_83
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DOI: https://doi.org/10.1007/978-1-4613-1717-3_83
Publisher Name: Springer, Boston, MA
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