Abstract
The fluorescence of hematoporphyrin-derivative (HpD) or dihematoporphyrin ether (DHE), together with the property of attaining a higher concentration in malignant tumors than in most normal tissues, form a basis for diagnosis of cancer. Malignant tumors exhibit greater fluorescence than the surrounding nonmalignant tissue when excited by light of appropriate wavelength, and the tumor can be detected by a suitable imaging or nonimaging system. This paper discusses the fluorescent agent and background fluorescence, excitation systems, imaging methods, and nonimaging methods for diagnosis of cancer.
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© 1985 Plenum Press, New York
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Profio, A.E., Balchum, O.J. (1985). Fluorescence Diagnosis of Cancer. In: Kessel, D. (eds) Methods in Porphyrin Photosensitization. Advances in Experimental Medicine and Biology, vol 193. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2165-1_6
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DOI: https://doi.org/10.1007/978-1-4613-2165-1_6
Publisher Name: Springer, Boston, MA
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