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Brief Communication HLA-Antigens in NPC Patients from a Low — Risk Area (Cologne, FRG)

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Epstein-Barr Virus and Associated Diseases

Part of the book series: Developments in Medical Virology ((DIMV,volume 1))

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Summary

HLA typing of 76 low-risk patients with malignant tumors of the nasopharynx (n = 65) and histomorphologically identical carcinomas of the mesopharyngeal region (n = 11) showed no significantly different frequency of any HLA-antigen. A slight elevation of B-27 was shown for so-called lympholepithelial carcinomas of the nasopharyngeal region. Neither HLA Bw46 (Sin-2) nor any other NPC-linked antigen of high-risk groups has been found in our patients. Apparently, susceptibility to NPC in the Caucasian ethnic group is neither determined nor codetermined by class I antigens of the HLA system.

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Author information

Authors and Affiliations

  1. ENT — Clinic of the University of Hamburg, Germany

    G. Bertram

  2. Department of Transfusion Medicine, University of Cologne, Germany

    J. Kruger

  3. ENT — Clinic of the University of Hamburg, Germany

    K. Sesterhenn

Authors
  1. G. Bertram
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  2. J. Kruger
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  3. K. Sesterhenn
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Editor information

P. H. Levine D. V. Ablashi G. R. Pearson S. D. Kottaridis

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© 1985 Martinus Nijhoff Publishing, Boston

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Bertram, G., Kruger, J., Sesterhenn, K. (1985). Brief Communication HLA-Antigens in NPC Patients from a Low — Risk Area (Cologne, FRG). In: Levine, P.H., Ablashi, D.V., Pearson, G.R., Kottaridis, S.D. (eds) Epstein-Barr Virus and Associated Diseases. Developments in Medical Virology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2625-0_19

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  • DOI: https://doi.org/10.1007/978-1-4613-2625-0_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9641-6

  • Online ISBN: 978-1-4613-2625-0

  • eBook Packages: Springer Book Archive

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