Abstract
Resting T lymphocytes when activated by exposure to antigen or mitogen induce and amplify their own proliferation by producing a glycoprotein hormone called T cell growth factor or inteiieukin 2 (IL2) [1]. One of the classical markers of activated T cells is the subseqent expression of specific membrane receptors for interleukin 2 (IL2R) [2]. The expression of these receptors on T cells was shown to be a transient event [3] and restimulation with either antigen or mitogen is required for continous IL2R expression and maintainance of T cell proliferative capacity.
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Ruhl, S., Begley, G.C., Bickel, M., Pluznik, H. (1990). Interleukin-2 Receptors on Monocytes and Their Relation to the Process of Monocytic Cell Differentiation. In: Gorin, N.C., Douay, L. (eds) Experimental Hematology Today—1989. Experimental Hematology Today—1989, vol 1989. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9003-9_6
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DOI: https://doi.org/10.1007/978-1-4613-9003-9_6
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