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Bioinspired Nanoscale Water Channel and its Potential Applications

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Bioinspiration

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

The dynamics of water molecules confined in nanochannels is of great importance for designing novel molecular devices/machines/sensors, which have wide applications in nanotechnology, such as water desalination, chemical separation, sensing. In this chapter, inspired by the aquaporins, which are proteins embedded in the cell membrane that regulate the flow of water but stop the protons, we will discuss the mechanism of water channel gating and water channel pumping, where water molecules form single-filed structure. The single-filed water molecules can also serve as molecular devices for signal transmission, conversion, and multiplication. Moreover, the water in the channel may have great potential applications in designing the lab-in-tube to controllable manipulation of biomolecules.

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Authors and Affiliations

  1. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, No.2019 Baojia Road, 800-204, Shanghai, 201800, China

    Haiping Fang, Chunlei Wang & Rongzheng Wan

  2. Department of Physics, Zhejiang Normanl University, Jinhua, 321004, China

    Hangjun Lu

  3. Institute of Systems Biology, Shanghai University, Shanghai, 200444, China

    Yusong Tu

  4. Bio-X Lab, Department of Physics, Zhejiang University, Hangzhou, 310027, China

    Peng Xiu

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  1. Haiping Fang
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  2. Chunlei Wang
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  4. Hangjun Lu
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  6. Peng Xiu
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Correspondence to Haiping Fang .

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  1. Faculty of Sciences, Dept. of Physics, National Univ. of Singapore, Science Drive 3 2, Singapore, 117542, Singapore

    Xiang Yang Liu

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Fang, H., Wang, C., Wan, R., Lu, H., Tu, Y., Xiu, P. (2012). Bioinspired Nanoscale Water Channel and its Potential Applications. In: Liu, X. (eds) Bioinspiration. Biological and Medical Physics, Biomedical Engineering. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5372-7_1

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