Skip to main content

Major Anesthetic Themes in the 1970s

  • Chapter
The Wondrous Story of Anesthesia

Abstract

Increasing anesthesiologist numbers and diversity in the 1970s led to subspecialty societies and journals. Women constituted a rising fraction of anesthesiolgists. The practice of anesthesia became more diverse with an expanding application of outpatient surgery, establishment of regional anesthesia in everyday practice, and a rising use of anesthesia outside the operating room. Our understanding of anesthetic drugs and how to best use them changed. In the US, and to a lesser extent elsewhere, the minimally hepatotoxic enflurane replaced halothane. We explored neuromuscular pharmacokinetics and clinically defined recovery from neuromuscular blockade. Dantrolene treatment of malignant hyperthermia was initiated. We incorrectly thought we might understand how inhaled anesthetics acted. We found opioid receptors in the spinal cord, leading to intrathecal opioid administration to provide analgesia. Patients received opioid analgesia on demand.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Judy Donegan became the first woman ABA Director in 1983, and Betty Stephenson, the first woman ASA President in 1991. Jane Fitch became President-elect of the ASA in 2012.

References

  1. Bunker JP, Forrest WH, Moesteller F, Vandam L. The national halothane study. Bethesda: National Institutes of Health; 1969.

    Google Scholar 

  2. Mazze RI, Cousins MJ. Renal toxicity of anaesthetics: with specific reference to the nephrotoxicity of methoxyflurane. Canad Anaesth Soc J. 1973;20:64–80.

    Article  CAS  PubMed  Google Scholar 

  3. Eger EI II, Smuckler EA, Ferrell LD, Goldsmith CH, Johnson BH. Is enflurane hepatotoxic? Anesth Analg. 1986;65:21–30.

    Article  PubMed  Google Scholar 

  4. Corbett TH. Cancer and congenital anomalies associated with anesthetics. Ann NY Acad Sci. 1976;271:58–66.

    Article  CAS  PubMed  Google Scholar 

  5. Eger EI II, White AE, Brown CL, Biava CG, Corbett TH, Stevens WC. A test of the carcinogenicity of enflurane, isoflurane, halothane, methoxyflurane, and nitrous oxide in mice. Anesth Analg. 1978;57:678–94.

    CAS  PubMed  Google Scholar 

  6. Michenfelder JD, Theye RA. Cerebral protection by thiopental during hypoxia. Anesthesiology. 1973;39:510–7.

    Article  CAS  PubMed  Google Scholar 

  7. Rowland M, Benet L, Graham G. Clearance concepts in pharmacokinetics. J Pharmacokinet Biopharm. 1973;1:123–36.

    Article  CAS  PubMed  Google Scholar 

  8. Sheiner LB, Beal SL. Evaluation of methods for estimating population pharmacokinetics parameters. I. Michaelis-Menten model: routine clinical pharmacokinetic data. J Pharmacokinet Biopharm. 1980;8:553–71.

    Article  CAS  PubMed  Google Scholar 

  9. Sheiner LB, Stanski DR, Vozeh S, Miller RD, Ham J. Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther. 1979;25:358–71.

    CAS  PubMed  Google Scholar 

  10. Ali HH, Utting JE, Nightingale DA, Gray C. Quantitative assessment of residual curarization in humans. Br J Anaesth. 1970;42:802–3.

    CAS  PubMed  Google Scholar 

  11. Kehlet H. Clinical course and hypothalamic-pituitary-adrenocortical function in glucocorticoid-treated patients. Copenhagen: FADL’s Forlag; 1976.

    Google Scholar 

  12. Prentiss JE. Cardiac arrest following caudal anesthesia. Anesthesiology. 1979;50:51–3.

    Article  CAS  PubMed  Google Scholar 

  13. Sechzer PH. Objective measurement of pain. Anesthesiology. 1968;29:109–10. (abstract).

    Article  Google Scholar 

  14. Forrest WH Jr, Smethurst PW, Kienitz ME. Self-administration of intravenous analgesics. Anesthesiology. 1970;33:363–5.

    Article  PubMed  Google Scholar 

  15. White WD, Pearce DJ, Norman J. Postoperative analgesia: a comparison of intravenous on-demand fentanyl with epidural bupivacaine. Br Med J. 1979;2:166–7.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  16. Pert CB, Snyder SH. Opiate receptor: demonstration in nervous tissue. Science. 1973;179:1011–4.

    Article  CAS  PubMed  Google Scholar 

  17. Duggan AW, Hall JG, Headley PM. Morphine, enkephalin and the substantia gelatinosa. Nature. 1976;264:456–8.

    Article  CAS  PubMed  Google Scholar 

  18. Yaksh TL, Rudy TA. Analgesia mediated by a direct spinal action of narcotics. Science. 1976;192:1357–8.

    Article  CAS  PubMed  Google Scholar 

  19. Behar M, Magora F, Olshwang D, Davidson JT. Epidural morphine in treatment of pain. Lancet. 1979;1:527–9.

    Article  CAS  PubMed  Google Scholar 

  20. Wang JK, Nauss LA, Thomas JE. Pain relief by intrathecally applied morphine in man. Anesthesiology. 1979;50:149–51.

    Article  CAS  PubMed  Google Scholar 

  21. Matas R. Local and regional anesthesia with cocain and other analgesic drugs, including the subarachanoid method, as applied in general surgical practice. Philadelphia Med J. 1900;6:820–43.

    Google Scholar 

  22. Cousins MJ, Mather LE, Glynn CJ, Wilson PR, Graham JR. Selective spinal analgesia. Lancet. 1979;1:1141–2.

    Article  CAS  PubMed  Google Scholar 

  23. Szeto A. Mike Ramsey’A medical device entrepreneur. Engineering Med Biol. 2002;21:12–3.

    Article  Google Scholar 

  24. Ball CM, Westhorpe RN. Historical notes on anaesthesia and intensive care. 2–12. Sydney: Australian Society of Anaesthetists; 2012. pp 228–9.

    Google Scholar 

  25. Scurr CF. Evolution and revolution in anaesthetic training. Ann R Coll Surg Engl. 1971;48:274–92.

    CAS  PubMed Central  PubMed  Google Scholar 

  26. Wylie WD. There, but for the grace of God…’. Ann R Coll Surg Engl. 1975;56:171–80.

    CAS  PubMed Central  PubMed  Google Scholar 

  27. Vassalo SA. Lewis H Wright memorial lecture. ASA Newsletter. 2001;75:22–4.

    Google Scholar 

  28. Cooper JB, Newbower RS. The anesthesia machine’an accident waiting to happen. In: Pickett M, Triggs TJ, editors. Human factors in health care. Lexington: DC Heath & Co; 1975. pp. 345–58.

    Google Scholar 

  29. Cooper JB, Newbower RS, Long CD, McPeek B. Preventable anesthesia mishaps: a study of human factors. Anesthesiology. 1978;49:399–406.

    Article  CAS  PubMed  Google Scholar 

  30. Cooper JB, Newbower RS, Moore JW, Trautman ED. A new anesthesia delivery system. Anesthesiology. 1978;49:310–8.

    Article  CAS  PubMed  Google Scholar 

  31. Viljoen JF, Estafanous FG, Kellner GA. Propranolol and cardiac surgery. J Thorac Cardiovasc Surg. 1972;64:826–30.

    CAS  PubMed  Google Scholar 

  32. Prys-Roberts C, Foex P, Biro GP, Roberts JG. Studies of anaesthesia in relation to hypertension. V. Adrenergic beta-receptor blockade. Br J Anaesth. 1973;45:671–81.

    Article  CAS  PubMed  Google Scholar 

  33. Vaisman AI. [Working conditions in the operating room and their effect on the health of anesthetists]. Eksp Khir Anesteziol. 1967;12:44–9.

    Google Scholar 

  34. Ericson A, Kallen B. Survey of infants born in 1973 or 1975 to Swedish women working in operating rooms during their pregnancies. Anesth Analg. 1979;58:302–5.

    Article  CAS  PubMed  Google Scholar 

  35. Spence AA. Environmental pollution by inhalation anaesthetics. Br J Anaesth. 1987;59:96–103.

    Article  CAS  PubMed  Google Scholar 

  36. Ashbaugh DG, Bigelow DB, Petty TL, Levine BE. Acute respiratory distress in adults. Lancet. 1967;2:319–23.

    Article  CAS  PubMed  Google Scholar 

  37. http://www.maquet.com/content/Documents/Site_Specific/MAQUETcom/GENERAL_The_Servo_Story.pdf

  38. Watson WF. Development of the PVC endotracheal tube. BioMaterials. 1980;1:41–6.

    Article  CAS  PubMed  Google Scholar 

  39. Calverley RK. Intubation in anaesthesia. In: Atkinson RS, Boulton TB, editors. The History of Anaesthesia. London: Royal Society of Medicine; 1989. pp. 333–41.

    Google Scholar 

  40. Russell CA. Developments in thermoplastic tracheal tubes. In: Barr AM, Boulton TB, Wilkinson DJ, editors. Essays on the History of Anaesthesia. London: Royal Society of Medicine; 1996. pp. 94–7.

    Google Scholar 

  41. Geffin B, Pontoppidan H. Reduction of tracheal damage by the prestretching of inflatable cuffs. Anesthesiology. 1969;31:462–3.

    Article  CAS  PubMed  Google Scholar 

  42. Ring WH. RAE (Ring, Adair, Elwyn) endotracheal tubes: wallace Harold Ring (1932-). In: Maltby JR, editor. Notable Names in Anaesthesia. London: Royal Society of Medicine; 2002. pp. 167–9.

    Google Scholar 

  43. Stiles CM, Stiles QR, Denson JS. A flexible fiber optic laryngoscope. JAMA. 1972;221:1246–7.

    Article  CAS  PubMed  Google Scholar 

  44. Nicoll JH. The surgery of infancy. Br Med J. 1909;18:753–4.

    Google Scholar 

  45. Waters RM. The down-town anesthesia clinic. Am J Surg. 1919;39 (suppl):71–3.

    Google Scholar 

  46. Berrill TH. A year in the life of a surgical day unit. Br Med J. 1972;4:348–9.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  47. Reed WA, Ford JL. Development of an independent outpatient surgical center. Int Anesthesiol Clin. 1976;14:113–30.

    Article  CAS  PubMed  Google Scholar 

  48. Kalow W, Britt BA, Terreau ME, Haist C. Metabolic error of muscle metabolism after recovery from malignant hyperthermia. Lancet . 1970;2:895–8.

    Article  CAS  PubMed  Google Scholar 

  49. Ellis FR, Harriman DG, Keaney NP, Kyei-Mensah K, Tyrrell JH. Halothane-induced muscle contracture as a cause of hyperpyrexia. Br J Anaesth. 1971;43:721–2.

    CAS  PubMed  Google Scholar 

  50. Harrison GG. Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium. Br J Anaesth. 1975;47:62–5.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rod N. Westhorpe OAM MB BS FRCA FANZCA .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Edmond I Eger, MD

About this chapter

Cite this chapter

Westhorpe, R., Saidman, L., Eger II, E. (2014). Major Anesthetic Themes in the 1970s. In: Eger II, E., Saidman, L., Westhorpe, R. (eds) The Wondrous Story of Anesthesia. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8441-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-8441-7_10

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-8440-0

  • Online ISBN: 978-1-4614-8441-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics