Abstract
Normal cells possess mechanisms that protect them from the action of oncogenes. Thus, normal primary cells are not affected by neoplastic transformations, whereas the majority of immortal cells used in laboratory cultures have acquired mutations during the immortalization process and are susceptible to being transformed. Our main interest is the study of the molecular mechanisms which signal anti-tumor responses as well as the impact these anti-tumor responses have upon the cell cycle.
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Serrano, M. (2003). Proliferation: The Cell Cycle. In: Llombart-Bosch, A., Felipo, V. (eds) New Trends in Cancer for the 21st Century. Advances in Experimental Medicine and Biology, vol 532. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0081-0_2
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DOI: https://doi.org/10.1007/978-1-4615-0081-0_2
Publisher Name: Springer, Boston, MA
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