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Progestins Have Actions Through GABAA Receptors

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The Identities of Membrane Steroid Receptors

Abstract

Progesterone (P) mediates reproductive behavior in rodents through actions at y-aminobutyric acid (GABAA)/benzodiazepine receptor complexes (GBRs) in the ventral tegmental area (VTA). Data show P does not act at cognate intracellular progestin receptors (PRs) in the VTA, but may have membrane actions at GBRs due to 5α-pregnan-3α-ol-20-one (3α,5α-THP).

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© 2003 Springer Science+Business Media New York

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Frye, C.A., Petralia, S.M. (2003). Progestins Have Actions Through GABAA Receptors. In: Watson, C.S. (eds) The Identities of Membrane Steroid Receptors. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0339-2_20

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  • DOI: https://doi.org/10.1007/978-1-4615-0339-2_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5028-6

  • Online ISBN: 978-1-4615-0339-2

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