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The Microphysiology of Lung Liquid Clearance

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Control of the Cardiovascular and Respiratory Systems in Health and Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 381))

Abstract

Pulmonary edema results from failure at essentially two levels of regulation in the lung microvascular bed, namely that of of liquid production by microvascular filtration and that of filtrate clearance from the interstitium. Of these, the regulation of filtration has attracted by far the greatest amount of interest. The reasons are not difficult to understand. In the sixties and seventies the burgeoning interest in the pulmonary circulation produced a number of elegant techniques for quantification of the determinants of lung microvascular filtration. To take some examples, the applications of the gravimetric, the lymph sampling and the indicator dilution techniques to the lung, advanced the quantification of the lung microvascular barrier and furthered the understanding of microvascular filtrate composition (reviewed in 27).

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Authors and Affiliations

  1. Departments of Medicine and Physiology, College of Physicians and Surgeons, Columbia University, St. Luke’s-Roosevelt Hospital Center, 1000 10th Avenue, New York, NY, 10019, USA

    Jahar Bhattacharya

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  1. Jahar Bhattacharya
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Editors and Affiliations

  1. University of California, Davis, Davis, California, USA

    C. Tissa Kappagoda  & Marc P. Kaufman  & 

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© 1995 Springer Science+Business Media New York

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Bhattacharya, J. (1995). The Microphysiology of Lung Liquid Clearance. In: Kappagoda, C.T., Kaufman, M.P. (eds) Control of the Cardiovascular and Respiratory Systems in Health and Disease. Advances in Experimental Medicine and Biology, vol 381. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1895-2_10

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  • DOI: https://doi.org/10.1007/978-1-4615-1895-2_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5773-5

  • Online ISBN: 978-1-4615-1895-2

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