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Aging, Comorbidity, and Breast Cancer Survival: An Epidemiologic View

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The Underlying Molecular, Cellular and Immunological Factors in Cancer and Aging

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 330))

Abstract

This is a review of epidemiologic studies, which suggest that comorbidity (e.g., diabetes and heart disease) has an adverse effect on survival among women with incident, invasive breast cancer, adjusting for chronological age and stage of breast cancer at diagnosis. As part of this review, recent results are presented from a series of 463 breast cancer cases, identified through the Metropolitan Detroit Cancer Surveillance System. Women with two or more concurrent health conditions were 2.2 times more likely than breast cancer cases without comorbidity to die from their breast cancer over a four-year period (95% CI: 1.13, 4.18). Limiting heart disease was especially problematic. Recommendations are made for future research in this area.

Support for this project was provided through NIA Grant RO1-AG-04969, NCI Contract N01-CN-55423, and by the United Foundation of Detroit.

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Authors and Affiliations

  1. School of Public Health, University of California at Berkeley, Berkeley, CA, 94720, USA

    William A. Satariano

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  1. William A. Satariano
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Editor information

Editors and Affiliations

  1. National Cancer Institute, Bethesda, Maryland, USA

    Stringner Sue Yang Ph.D.

  2. National Institute on Aging, Bethesda, Maryland, USA

    Huber R. Warner Ph.D.

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© 1993 Springer Science+Business Media New York

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Satariano, W.A. (1993). Aging, Comorbidity, and Breast Cancer Survival: An Epidemiologic View. In: Yang, S.S., Warner, H.R. (eds) The Underlying Molecular, Cellular and Immunological Factors in Cancer and Aging. Advances in Experimental Medicine and Biology, vol 330. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2926-2_1

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  • DOI: https://doi.org/10.1007/978-1-4615-2926-2_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6270-8

  • Online ISBN: 978-1-4615-2926-2

  • eBook Packages: Springer Book Archive

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