Skip to main content
SpringerLink
Log in

Ontogenetic Development of Cardiac Inotropic Responsiveness

  • Chapter
Heart Function in Health and Disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 140))

  • 37 Accesses

Abstract

Experimental data clearly indicate that significant ontogenetic differences exist in cardiovascular sensitivity to inotropic agents, both under “in vitro” and “in vivo” conditions (1). It seems likely that despite significant interspecies differences developmental changes may exist in all mammals depending on the degree of maturation of systems involved in the regulation of contractile function (2). This field of investigation was stimulated in recent years by an increasing clinical use of positive and negative inotropic drugs (e.g. catecholamines, calcium antagonists) during early phases of ontogenetic development, particularly during pregnancy in order to prevent premature labor or to treat acute intrapartum fetal distress (3, 4) or in pediatric cardiology (5, 6).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Driscoll D. J Clin Perinatol 1987;14:931–948.

    CAS  Google Scholar 

  2. Fabiato A, Fabiato F. Ann NY Acad Sci 1978;307:491–522.

    Article  PubMed  CAS  Google Scholar 

  3. Benedetti T, J Clin Perinatol 1986;13:843–852.

    CAS  Google Scholar 

  4. Harake B, Gilbert RD, Ashwal S, Power GG. Am J Obstet Gynecol 1987;157:1003–1008.

    PubMed  CAS  Google Scholar 

  5. Sapire DW, O’Riordan AC, Black IFS. Am J Cardiol 1981;48:1091–1097.

    Article  PubMed  CAS  Google Scholar 

  6. Cho C, Pruitt AW. Am J Dis Child 1986;140:360–366.

    PubMed  CAS  Google Scholar 

  7. Ostádal B, Beamish RE, Barwinsky J, Dhalla NS. J Appl Cardiol 1989;4:467–486.

    Google Scholar 

  8. Abinader E, Borowitz Z, Berger A, Helv Pediatr Acta 1981;36:451–455.

    CAS  Google Scholar 

  9. Wischnik A, Hotzinger B, Wischnik B, Schroll A, Trenkwalder V, Wiedenback A. Arzneim Forsch 1984;34:684–687.

    CAS  Google Scholar 

  10. Artman M, Kithas PA, Wike JS, Strada SJ. Am J Physiol 1988;255:H335–H342.

    PubMed  CAS  Google Scholar 

  11. Nakanishi T, Seguchi M, Takao A. Experientia 1988;44:936–944.

    Article  PubMed  CAS  Google Scholar 

  12. Swynghedauw B. Physiol Rev 1986;66:710–771.

    PubMed  CAS  Google Scholar 

  13. Langer GA. In: Calcium and the Heart (eds.) GA Langer. Raven Press Ltd, New York, 1990;355–378.

    Google Scholar 

  14. Tanaka H, Shigenobu K. J Mol Cell Cardiol 1989;21:1305–1313.

    Article  PubMed  CAS  Google Scholar 

  15. Schiebler TH, Wolf HH. Zellforsch 1966;69:22–40.

    Article  CAS  Google Scholar 

  16. Akera T. In: Calcium and the Heart (eds.) GA Langer. Raven Press Ltd, New York, 1990;299–331.

    Google Scholar 

  17. Park MK, Sheridan PH, Morgan WF, Beck N. Devol Pharmacol Ther 1980;1:70–82.

    CAS  Google Scholar 

  18. Rockson SG, Homey CJ, Quinn P, Manders WT, Haber E, Vatner S. J Clin Invest 1981;67:319–327.

    Article  PubMed  CAS  Google Scholar 

  19. Driscoll DJ, Fukushige J, Hartley CJ, Lewis RM, Entmann ML. Devel Pharmacol Ther 1981;2:91–103.

    CAS  Google Scholar 

  20. Nishioka K, Nakanishi T, George BL, Jarmakani JM. J Mol Cell Cardiol 1981;13:511–520.

    Article  PubMed  CAS  Google Scholar 

  21. Ostádal B, Skovránek J, Kolár F, Janatová T, Krause EG, Ostadálová I. Biomed Biochim Acta 1987;46:S522–S526.

    PubMed  Google Scholar 

  22. Skovránek J, Ostádal B, Pelouch V, Procházka J. Pediatr Cardiol 1986;7:25–29.

    Article  PubMed  Google Scholar 

  23. Kolár F, Ostádal ?, Papousek F. Basic Res Cardiol 1990;85:429–434.

    Article  PubMed  Google Scholar 

  24. Boucek RJ, Shelton ME, Artman M, Mushlin PS, Starnes VA, Olson RD. Pediatr Res 1984;18:948–952.

    Article  PubMed  CAS  Google Scholar 

  25. Seguchi M, Jarmakani JM, George BL, Harding JA. Pediatr Res 1986;20:838–842.

    Article  PubMed  CAS  Google Scholar 

  26. Ostádalová I, Kolár F, Rohlicek J, Rohlicek V, Procházka J, Ostádal B. J Mol Cell Cardiol 1992; (in press).

    Google Scholar 

  27. Kolár F, Cole WC, Ostádal B, Dhalla NS. Am J Physiol 1990;259:H712–H719.

    PubMed  Google Scholar 

  28. Renaud FJ, Kazazoglou T, Schmid A, Romey G, Lazdunski M. Eur J Biochem 1984;139:673–681.

    Article  PubMed  CAS  Google Scholar 

  29. Boucek RJ, Shelton ME, Artman M, Landon E. Basic Res Cardiol 1985;80:316–325.

    Article  PubMed  Google Scholar 

  30. Chizzonite RA, Zak R. J Biol Chem 1984;259:12628–12632.

    PubMed  CAS  Google Scholar 

  31. Lompre AM, Nadal-Ginard B, Mahdavi V. J Biol Chem 1984;259:6437–6446.

    PubMed  CAS  Google Scholar 

  32. Limas CJ. Am J Physiol 1978;235:H745–H751.

    PubMed  CAS  Google Scholar 

  33. Takacs IE, Nosztray K, Szabo J, Szentmiklos AJ, Cseppento A, Szegi J. Gen Physiol Biophys 1985;4:271–278.

    PubMed  CAS  Google Scholar 

  34. Kim D, Smith TW, Marsh JD. J Clin Invest 1987;80:88–94.

    Article  PubMed  CAS  Google Scholar 

  35. Daly MJ, Seppet EK, Vetter R, Dhalla NS. In: Subcellular Basis of contractile Failure (eds.) B Korecky, NS Dhalla. Kluwer Academic Publishers, Boston; 1990;173–191.

    Chapter  Google Scholar 

  36. Strauer BE, Schulze W. Bas Res Cardiol 1976;71:624–644.

    Article  CAS  Google Scholar 

  37. Marriott ML, McNeil JH. Can J Physiol Pharmacol 1983;61:1382–1390.

    Article  PubMed  CAS  Google Scholar 

  38. Pic P, Bouguin J-P. J Dev Physiol 1985;7:207–214.

    PubMed  CAS  Google Scholar 

  39. Vigouroux E. Acta Endocrinol 1976;83:752–762.

    PubMed  CAS  Google Scholar 

  40. Kolár F, Seppet EK, Vetter R, Procházka J, Grünermel J, Zilmer K, Ostádal B. Pflügers Arch 1991; (in press).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Physiology, Czechoslovak Academy of Sciences, University Hospital Motol, Prague, CZECHOSLOVAKIA

    B. Ostádal, F. Kolár & I. Ostádalová

  2. Kardiocentrum, University Hospital Motol, Prague, Czechoslovakia

    J. Skovránek

Authors
  1. B. Ostádal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Kolár
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Skovránek
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. I. Ostádalová
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institute of Physiology, Czechoslovak Academy of Sciences, Prague, Czechoslovakia

    Bohuslav Ostadal (Director) (Director)

  2. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Centre University of Manitoba, Winnipeg, Canada

    Naranjan S. Dhalla (Distinguished Professor and Head) (Distinguished Professor and Head)

Rights and permissions

Reprints and permissions

Copyright information

© 1993 Springer Science+Business Media New York

About this chapter

Cite this chapter

Ostádal, B., Kolár, F., Skovránek, J., Ostádalová, I. (1993). Ontogenetic Development of Cardiac Inotropic Responsiveness. In: Ostadal, B., Dhalla, N.S. (eds) Heart Function in Health and Disease. Developments in Cardiovascular Medicine, vol 140. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3090-9_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-3090-9_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6350-7

  • Online ISBN: 978-1-4615-3090-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation