Abstract
As in the Western countries, the incidence of coronary artery disease in diabetic patients is increasing in Japan. Early detection of coronary artery disease is important in the management of diabetic patients. However, because painless myocardial infarction is frequent in diabetics(l), silent ischemia might be also frequent in asymptomatic diabetic patients. Exercise electrocardiography is useful in the early detection of coronary artery disease, but no data was available concerning the incidence and prognostic significance of exercise electrocardiographic abnormalities in asymptomatic diabetic patients in Japan. To identify incidence and prognostic significance of exercise-induced abnormalities in asymptomatic Type 2 diabetic patients, we performed treadmill exercise stress tests in 176 consecutive patients with no symptoms and signs suggestive of cardiac disease and they were followed prospectively.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bradley RF, Schonfeld A. Diminished pain in diabetic patients with acute myocardial infarction. Geriatrics 1962;17:322–326.
Rifkin RD, Hood Jr WB. Bayesian analysis of electrocardiographic exercise stress testing. N Engl J Med 1977;297:681–686.
Uhl GS, Froelicher V. Screening for asymptomatic coronary artery disease. J Am Coll Cardiol 1983;1:946–955.
Lemp GF, Zwaag RV, Hughes JP, Maddock V, Kroetz F, Ramanathan KB, Mirvis DM, Sullivan JM. Association between the severity of diabetes mellitus and coronary arterial atherosclerosis. Am J Cardiol 1987;60:1015–1019.
Opasich C, Cobelli F, Assandri J, Calsamiglia G, Febo O, Larovere MT, Pozzoli M, Traversi E, Ardissino D, Specchia G. Incidence and prognostic significance of symptomatic and asymptomatic exercise-induced ischemia in patients with recent myocardial infarction. Cardiology 1984;71:284–291.
Persson G. Exercise tests in male diabetics. A nine-years’s follow-up study with special reference to ECG changes and cardiovascular morbidity. Acta Med Scand 1977; 605(suppl):7–23.
Rubier S, Gerber D, Reitano J, Chokshi V, Fisher VJ. Predictive value of clinical and exercise variables for detection of coronary artery disease in men with diabetes mellitus. Am J Cardiol 1987;59:1310–1313.
Gerson MC, Khoury JC, Hertzberg VS, Fischer EE, Scott RC. Prediction of coronary artery disease in a population of insulin-requiring diabetic patients: Results of an 8-year follow-up study. Am Heart J 1988;116:820–826.
Lozner EC, Morganroth J. New critieria to enhance predictability of coronary artery disease by exercise testing in asymptomatic subjects. Circ 1977;56:799–802.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer Science+Business Media New York
About this chapter
Cite this chapter
Kawakubo, K., Oku, J., Murakami, T., Sugimoto, T. (1992). Prognostic Significance of Treadmill Exercise Stress Test in Diabetic Patients Without Cardiovascular Signs. In: Nagano, M., Mochizuki, S., Dhalla, N.S. (eds) Cardiovascular Disease in Diabetes. Developments in Cardiovascular Medicine, vol 130. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3512-6_7
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3512-6_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6558-7
Online ISBN: 978-1-4615-3512-6
eBook Packages: Springer Book Archive