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Expression of mouse and frog rRNA genes: transcription and processing

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Molecular Mechanisms of Cellular Growth

Abstract

This article summarizes a number of lines of investigation of rRNA gene expression that are ongoing in the laboratory. These studies focus on mouse and frog, two distant vertebrate species. One major conclusion is that the basic properties of rRNA gene expression appear remarkably well conserved in evolution, with only relatively minor perturbations between frog and mouse, contrary to the common interpretation of the species-selectivety between mouse and human rDNA transcription (e.g., 1). This is true both for the process of rDNA transcription and for the subsequent rRNA processing event.

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© 1991 Springer Science+Business Media Dordrecht

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Sollner-Webb, B. et al. (1991). Expression of mouse and frog rRNA genes: transcription and processing. In: Morgan, H.E. (eds) Molecular Mechanisms of Cellular Growth. Developments in Molecular and Cellular Biochemistry, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3886-8_18

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  • DOI: https://doi.org/10.1007/978-1-4615-3886-8_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6733-8

  • Online ISBN: 978-1-4615-3886-8

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