Abstract
In man, and most mammals, the retina is supported by two vascular beds. The retinal circulation courses through the inner half of the retina, and the choroidal circulation lies behind the retina. The relative oxygen contributions and regulatory properties of the retinal and choroidal vascular beds have been studied in considerable detail,1,2,3,4 prompted largely by the high incidence of vascular based diseases of the retina. There is general agreement that the retinal circulation is capable of a high degree of regulation5 and that in contrast, the choroid generally exhibits little or no regulatory capacity.6
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Yu D-Y., S.J. Cringle, V.A. Alder, and E-N. Su. Intraretinal oxygen distribution in the rat as a function of systemic blood pressure. Am. J. Physiol. 1994;267(Heart Circ. Physiol.36): H2498–H
Pournaras, C.J., C.E. Riva, M. Tsacopoulos, and K. Strammer. Diffusion of O2 in the retina of anaesthetized miniature pigs in normoxia and hyperoxia. Exp. Eye Res. 1989;49: 347–360.
Yancey, C.M., and R. A. Linsenmeier. Oxygen distribution and consumption in the cat retina at increased intraocular pressure. Invest. Ophthalmol. Vis. Sci. 1989;29: 600–611.
Ahmed, J., R.D. Braun, R. Dunn Jr., and R.A. Linsenmeier. Oxygen distribution in the Macaque retina. Invest. Ophthalmol. Vis. Sci. 1993;34: 516–521.
Riva, C.E., J.E. Grunwald, and S.H. Sinclair. Laser doppler velocimetry study of the effect of pure oxygen breathing on retinal blood flow. Invest. Ophthalmol. Vis. Sci. 1983;24: 47–51.
Riva, CE., S.D. Cranstoun., J.E. Grunwald, and B.L. Petrig. Choroidal blood flow in the foveal region of the human ocular fundus. Invest. Ophthalmol. Vis. Sci. 1994;35: 4273–4281.
Chase, J. The evolution of retinal vascularization in mammals. A comparison of vascular and avascular retinae. Ophthalmol. 1982;89: 1518–1525.
Yu D-Y, Cringle SJ, Alder VA, and Su E-N. Intraretinal oxygen distribution and choroidal regulation in the avascular retina of the guinea pig. Am. J. Physiol. 1996;270 (Heart Circ. Physiol. 39): H965–H973.
Cringle SJ, Yu D-Y, Alder VA, and Su E-N. Oxygen consumption in the avascular guinea pig retina. Am. J. Physiol. 1996; 271 (Heart Circ. Physiol. 40): H1162–H1165.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Cringle, S., Yu, DY., Alder, V., Su, EN., Yu, P. (1998). Choroidal Regulation of Oxygen Supply to the Guinea Pig Retina. In: Hudetz, A.G., Bruley, D.F. (eds) Oxygen Transport to Tissue XX. Advances in Experimental Medicine and Biology, vol 454. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4863-8_46
Download citation
DOI: https://doi.org/10.1007/978-1-4615-4863-8_46
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-7206-6
Online ISBN: 978-1-4615-4863-8
eBook Packages: Springer Book Archive