Abstract
Human tear lipocalin, secreted by the main lacrimal gland, belongs to a group of proteins able to bind lipophiles by enclosing them within their structures. We have recently reported the chromosomal location of the gene for human tear lipocalin (LCN1) on the long arm of chromosome 9 by in situ hybridization and somatic hybrid analysis.1,2 These results confirmed the localization of the same tear lipocalin gene by Glasgow et a1.,3 although these workers did not use the gene symbol LCN1. These data together also definitively proved that LCN1 is not assigned to chromosome 8, as erroneously reported by Redl’s team.4 We describe a dinucleotide polymorphism in the 3’ region of the tear lipocalin gene, which is known to span 6.2 kb and contains 7 exons.5
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References
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Lacazette, E., Pitiot, G., Mallet, J., Gachon, AM.F. (1998). Dinucleotide Repeat Polymorphism Near the Tear Lipocalin Gene. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_13
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DOI: https://doi.org/10.1007/978-1-4615-5359-5_13
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