Skip to main content

Abstract

Responses to exercise with one and several muscle groups allows for evaluation of integrative aspects of human physiology. One such area which has received much attention is the cardiovascular system. Exercise is an effective intervention as it not only brings various components of the system to function at its upper limits, but also gives clues to which variables that are primarily regulated. The focus here will be on muscle mass involvement in the exercise and the interplay between oxygen delivery and blood pressure.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Andersen, P., and B. Saltin, B. Maximal perfusion of skeletal muscle in man. J. Physiol. Lond. 366:233–249, 1985.

    PubMed  CAS  Google Scholar 

  2. Åstrand, P.-O., and B. Saltin. Maximal oxygen uptake and heart rate in various types of muscular activity. J. Appl. Physiol. 16:977–981, 1961.

    PubMed  Google Scholar 

  3. Clausen, J.P. Circulatory adjustments to dynamic exercise and effects of physical training in normal subjects and in patients with coronary artery disease. Prog. Cardiovas. Dis. 18:459–495, 1976.

    Article  CAS  Google Scholar 

  4. Donald, D.E., D.J. Rowlands, and D.A. Ferguson. Similarity of blood flow in the normal and the sympathectomiced dog limb during graded exercise. Clin. Res. 26:185–199, 1970.

    CAS  Google Scholar 

  5. Gulløv, A.L., F. Pott, B.K. Koefoed, P. Peteren, and N.H. Secher. Transcranial Doppler determined cerebral arterial blood velocity during cycling in arterial fibrillation. XV Nor. Cong. Cardiol., Malmø, Sweden, 1995, p. 37.

    Google Scholar 

  6. Hellström, G., G. Magnusson, B. Saltin, and N.G. Wahlgren. Cerebral haemodynamic effects of physical exercise in patients with chronic heart failure (abstract). Nord. Neurol. Soc. 1994.

    Google Scholar 

  7. Hermansen, L. Oxygen transport during exercise in human subjects. Acta Physiol. Scand. Supp. 299:1–104, 1973.

    Google Scholar 

  8. Holmgren, A. Circulatory changes during muscular work in man. Scand. J. Clin. Lab. Invest. 8: suppl. 24., 1956.

    Google Scholar 

  9. Kim, C.K., S. Strange, J. Bangsbo, and B. Saltin. Skeletal muscle perfusions in electrically induced dynamic exercise in humans. Acta Physiol Scand 153; 279–287, 1995.

    Article  PubMed  CAS  Google Scholar 

  10. Magnusson, G., L. Kaijser, C. Sylven, K.-E. Karlberg, B. Isberg, and B. Saltin. Peak skeletal muscle perfusion is maintained in patients with chronic heart failure. In press 1995.

    Google Scholar 

  11. Pawelczyk, J.A., B. Hanel, R.A. Pawelczyk, J. Warberg, and N.H. Secher. Leg vasoconstriction during dynamic exercise with reduced cardiac output. J. Appl. Physiol. 73:1838–1846, 1992.

    PubMed  CAS  Google Scholar 

  12. Richardson, R.S., D.C. Poole, D.R. Knight, S.S. Kurdak, M.C. Hogan, B. Grassi, E.C. Johnson, K.F. Kendrick, B.K. Erickson, and P.D. Wagner. High muscle blood flow in man: is maximal O2 extraction compromised? J. Appl Physiol. 75:1911–1916, 1993.

    PubMed  CAS  Google Scholar 

  13. Richter, E.A., B. Kiens, M. Hargreaves, and M. Kjær. Effects of arm-cranking on leg blood flow and noradrenaline spillover during leg exercise in man. Acta Physiol Scand. 144:9–14, 1992.

    Article  PubMed  CAS  Google Scholar 

  14. Rowell, L.B., B. Saltin, B. Kiens, and N.J. Christensen. Is peak quadriceps blood flow in humans even higher during exercise with hypoxemia. Am. J. Physiol. 251:H1038–H1044, 1986.

    PubMed  CAS  Google Scholar 

  15. Rørdam P., H.L. Olesen, J. Sindrup, and N.H. Secher. Effect of epidural anaesthesia on dorsal pedis arterial diameter and blood flow. Clin Physiol 15: 143–149, 1995.

    Article  PubMed  Google Scholar 

  16. Saltin, B. Aerobic and anaerobic work capacity at an altitude of 2,250 meters. In: Proc. Symp. on Physical Performance at Altitude, edited by U. Luft, 1967, pp. 97–102.

    Google Scholar 

  17. Saltin, B. Malleability of the system in overcoming limitations: functional elements. J. Exp. Biol. 115: 345–354, 1985.

    PubMed  CAS  Google Scholar 

  18. Saltin, B. Maximal oxygen uptake; limitation and malleability. In: International Perspectives in Exercise Physiology, edited by K. Nazar, R.L. Terjung, H. Kaciuba-Uscilko, and L. Budohoski. Champaign, USA: Human Kinetics, 1990, pp. 26–40.

    Google Scholar 

  19. Saltin, B., and P.D. Gollnick. Skeletal muscle adaptability: significance for metabolism and performance. In: Handbook of Physiology: Skeletal Muscle, sect. 10, edited by L.D. Peachey, R.H. Adrian, and S.R. Geiger. Bethesda, USA: Amer. Physiol. Soc., 1983, pp 555–631.

    Google Scholar 

  20. Savard, G.K., E.A. Richter, S. Strange, B. Kiens, N.J. Christensen, and B. Saltin. Norepinephrine spillover from skeletal muscle during exercise in humans: role of muscle mass. Am. J. Physiol. 257:H 1812–H1818, 1989.

    CAS  Google Scholar 

  21. Schmidt T.A., H. Bundgaard, H.L. Olesen, N.H. Secher, and K. Kjeldsen. Digoxin affects potassium homeostasis during exercise in patients with heart failure. Cardiovas. Res. 29: 506–511, 1995.

    CAS  Google Scholar 

  22. Secher, N.H., J.P. Clausen, K. Klausen, I. Noer, and J. Trap-Jensen. Central and regional circulatory effects of adding arm exercise to leg exercise. Acta Physiol. Scand. 100:288–297, 1977.

    Article  PubMed  CAS  Google Scholar 

  23. Secher, N.H., J. Jacobsen, D.B. Friedman, and S. Matzen. Bradycardia during reversible hypovolaemic shock: associated endocrine changes and clinical implications. Clin. Exp. Pharm. Physiol. 19:733–743, 1992.

    Article  CAS  Google Scholar 

  24. Secher, N.H., and Oddershede, I. Maximal oxygen uptake during swimming and bicycling. In: Swimming II, edited by L. Lewillie and J.P. Clarys. Baltimore, USA: Univ. Park Press, 1975, pp 137–142.

    Google Scholar 

  25. Secher, N.H., N. Ruberg-Larsen, R.A. Binkhorst, and F. Bonde-Petersen. Maximal oxygen uptake during arm and combined arm plus leg exercise. J. Appl. Physiol. 36:315–318, 1974.

    Google Scholar 

  26. Sinoway L.I., T.I. Musch, J.R. Minotti, and R. Zelis. Enhanced maximal metabolic vasodilatation in the dominant forearms of tennis players. J. Appl. Physiol. 61:673–678, 1986.

    PubMed  CAS  Google Scholar 

  27. Sinoway, L., and S. Prophet. Skeletal muscle metaboreceptor stimulation opposes peak metabolic vasodilation in humans. Cir. Res. 66:1576–1586, 1990.

    Article  CAS  Google Scholar 

  28. Sinoway L.I., J. Shenberger, J.S. Wilson, D. McLaughlin, T. Musch, and R.A. Zelis. 30-day forearm work protocol increases maximal forearm blood flow. J. Appl. Physiol. 62:1063–1067, 1987.

    PubMed  CAS  Google Scholar 

  29. Snell, P.G., W.H. Martin, J.C. Burckey, and CG. Blomqvist. Maximal vascular leg conductance in trained and untrained men. J. Appl. Physiol. 62:606–610, 1987.

    PubMed  CAS  Google Scholar 

  30. Strandell, T., and J.T. Shepherd. The effect in humans of increased sympathetic activity on the blood flow to active muscles. Acta Med. Scand. Supp. 472:146–167, 1967.

    CAS  Google Scholar 

  31. Strange, S., N.H. Secher, J.A. Pawelczyk, J. Kappakka, N.J. Christensen, J.H. Mitchell, and B. Saltin. Neural control of cardiovascular responses and of ventilation during dynamic exercise in man. J. Physiol. (Lond.) 470:693–704, 1993.

    CAS  Google Scholar 

  32. Taylor, H.L., E. Buskirk, and A. Henchel. Maximal oxygen intake as an objective measure of cardiorespiratory performance. J. Appl. Physiol. 8:73–80, 1955.

    PubMed  CAS  Google Scholar 

  33. Thompson, L.P., and D.E. Mohrman. Blood flow and oxygen consumption in skeletal muscle during sympathetic stimulation. Am. J. Physiol. 245:H66–H71, 1983.

    PubMed  CAS  Google Scholar 

  34. Wieling, W., and J.J. van Lieshout. Circulatory adaptation upon standing. In: New Trends in Autonomic Nervous System Research, edited by M. Yoshikawa, M. Uono, H. Tanabe, and S. Ishikawa. Amsterdam, Excerpta Medica, 1991, pp. 200–204.

    Google Scholar 

  35. Williamson, J.W., J.H. Mitchell, H.L. Olesen, P. Raven, and N.H. Secher. Reflex increase in blood pressure induced by leg compression in man. J. Physiol (Lond.) 475: 351–357, 1994.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

Secher, N.H., Saltin, B. (1996). Blood Flow Regulation During Exercise in Man. In: Steinacker, J.M., Ward, S.A. (eds) The Physiology and Pathophysiology of Exercise Tolerance. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5887-3_14

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5887-3_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7700-9

  • Online ISBN: 978-1-4615-5887-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics