Abstract
The adenosine receptor involved in the excitatory effect of this nucleoside on respiration mediated through carotid body chemoreceptors has been characterised in in vivo experiments, and exhibits agonist (Monteiro & Ribeiro, 1987) and antagonist (Ribeiro & Monteiro, 1991) profiles which are compatible with the presence of an A2 adenosine receptor subtype. The A2 adenosine receptors have been defined on the basis of their ability to stimulate adenyl cyclase and cAMP production (Fredholm et al, 1994). The present work was undertaken to investigate in vitro the effect of adenosine on cAMP content of the rat carotid body.
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© 1996 Springer Science+Business Media New York
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Monteiro, E.C., Vera-Cruz, P., Monteiro, T.C., Silva E Sousa, M.A. (1996). Adenosine Increases the cAMP Content of the Rat Carotid Body In Vitro . In: Zapata, P., Eyzaguirre, C., Torrance, R.W. (eds) Frontiers in Arterial Chemoreception. Advances in Experimental Medicine and Biology, vol 410. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5891-0_45
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DOI: https://doi.org/10.1007/978-1-4615-5891-0_45
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