Skip to main content
SpringerLink
Log in

Functional Markers for Fetal and Postnatal Differentiation of Rat Leydig Cells

  • Chapter
The Fate of the Male Germ Cell

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 424))

Abstract

The aim of the present work was to establish morphological markers for the functional differentiation of Leydig cells in rat in order to study the origin, development and maturation of these cells. Two different populations of Leydig cells can be observed in the rat testis from embryonic period till adulthood (Lording and de Kretser, 1972, Koupio et al. 1989; Teerds, 1989; Haider et al. 1986, 1995, Majdic et al. 1995)): 1. Fetal-Type Ley-dig cells (FTLC). 2. Adult-Type Leydig Cells (ATLC). Here is a summary of our results.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Chernes H, Cigorraga S. Dym M., Musse M, Pellizari E. Schteingart H & Venara M 1994 Isolation and characterization of mesenchymal cell fraction of Leydig cell precursors from adult EDS-treated rats. 8th European Workshop on Molecular and Cellular Endocrinology of Testis. De Panne (Belgium), p. 9.

    Google Scholar 

  • Haider SG, Passia D & Overmeyer G 1986 Studies on the fetal and postnatal development of rat Leydig cells employing Sß-hydroxy steroid dehydrogenase activity. Acta Histochemica. 32: 187–202.

    Google Scholar 

  • Haider SG, Laue D. Schwochau G & Hilscher B 1995 Morphological studies on the origin of adult-type Leydig cells in rat testis. Italian Journal of Anatomy and Embryology 100: 535–541.

    PubMed  Google Scholar 

  • Koupio T. Tapanainen J. Pelliniemi LJ & Huhtaniemi I. 1989 Development stages of fetal-type Leydig cells in prepuberal rats. Development 107: 213–220.

    Google Scholar 

  • Lording DW & de Kretser DM 1972 Comparative ultrastructural and histochemical studies of the interstitial cells of rat testis during fetal and postnatal development. Journal of Reproduction and Fertility 29: 261–269.

    Article  PubMed  CAS  Google Scholar 

  • Majdic G, Millar MR & Saunders PTK 1995 immunolocalization of androgen receptor to interstitial cells in fetal rat testes and to mesenchymal and epithelial cells of associated ducts. Journal of Endocrinology 147: 285–293.

    Article  PubMed  CAS  Google Scholar 

  • Schulze W, Davidoff MS, Ivell R & Holstein AF 1991 Neuron-specific enolase-like immunoreactivity in human Leydig cells. Andrologia 23: 279–283.

    Article  PubMed  CAS  Google Scholar 

  • Teerds K 1989 Aspects of Leydig cell development in the rat testis. Ph.D. thesis. Faculty of Biology, University of Utrecht (Netherlands): 1–135.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Anatomy II, Heinrich Heine University, POB 101007, 40001, Düsseldorf, Germany

    S. G. Haider, G. Servos, S. Tajtaraghi & G. Berthold

  2. Institute for Hormone and Fertility Research at the University Hamburg, Grandweg 64, 22529, Hamburg, Germany

    A. K. Mukhopadhyay

  3. Institute of Anatomy, University Hospital Hamburg Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Germany

    N. Kilic & S. Ergün

Authors
  1. S. G. Haider
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Servos
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Tajtaraghi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Berthold
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. K. Mukhopadhyay
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. N. Kilic
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. S. Ergün
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institute for Hormone and Fertility Research, University of Hamburg, Hamburg, Germany

    Richard Ivell

  2. Anatomical Institute, University of Hamburg, Hamburg, Germany

    Adolf-Friedrich Holstein

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer Science+Business Media New York

About this chapter

Cite this chapter

Haider, S.G. et al. (1997). Functional Markers for Fetal and Postnatal Differentiation of Rat Leydig Cells. In: Ivell, R., Holstein, AF. (eds) The Fate of the Male Germ Cell. Advances in Experimental Medicine and Biology, vol 424. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5913-9_23

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5913-9_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7711-5

  • Online ISBN: 978-1-4615-5913-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation