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The Kidney in Systemic Disease

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Contemporary Nephrology

Abstract

Our understanding of the mechanisms by which systemic diseases lead to alterations in renal function must rest on profound knowledge of normal physiology. In Volume 1 of this series, an attempt was made to employ three schemes which would allow us to predict, treat, or correct the renal manifestations of systemic illness. The schemes were based on the idea that composition changes in blood or alterations in the volume of the fluid compartments of the body inevitably affect the kidney. The schemes also took into consideration that the clinical manifestations of vascular and tubular disease will have their genesis depending on which part of the kidney (cortex versus medulla) is principally involved.1

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Martínez-Maldonado, M., Benabe, J.E., Novello, A. (1983). The Kidney in Systemic Disease. In: Klahr, S., Massry, S.G. (eds) Contemporary Nephrology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6722-6_11

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