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Humoral Response to Herpes Simplex Virus Infections

  • Chapter
The Herpesviruses

Part of the book series: The Viruses ((VIRS))

Abstract

Herpes simplex virus types 1 and 2 (HSV-1, HSV-2) give rise to a variety of human diseases of different severity and morbidity. It is well known that herpes virus remains latent in the human body after the first exposure to the virus (the primary infection) and colonizes either the trigeminal or the sacral ganglia, from where the virus is occasionally reactivated (for review see Wildy et al., 1982). The result of reactivation is either a clinical or a subclinical recurrent infection, and viral cellular proteins synthesized during a primary as well as during a recurrent infection interact with the immune system of the infected host organisms and give rise to the formation of both circulating HSV-specific antibodies and activated lymphocytes that have the potential to eliminate infectious virus from the infected host.

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  1. Institute of Medical Microbiology, University of Copenhagen, DK-2100, Copenhagen ø, Denmark

    Bodil Norrild

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  1. Bodil Norrild
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Editors and Affiliations

  1. University of Chicago, Chicago, Illinois, USA

    Bernard Roizman

  2. Sloan-Kettering Institute for Cancer Research, New York, New York, USA

    Carlos Lopez

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© 1985 Plenum Press, New York

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Norrild, B. (1985). Humoral Response to Herpes Simplex Virus Infections. In: Roizman, B., Lopez, C. (eds) The Herpesviruses. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8021-8_3

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  • DOI: https://doi.org/10.1007/978-1-4615-8021-8_3

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